Reds vs. Pirates Prediction, Odds, Picks - April 12

The Cincinnati Reds and Pittsburgh Pirates will meet on Saturday at Great American Ball Park, at 6:40 p.m. ET, with Elly De La Cruz and Ke'Bryan Hayes -- two hot hitters -- expected to deliver at the plate. The favored Reds have -128 moneyline odds to win against the underdog Pirates, who are listed at +108. Cincinnati is favored on the run line (-1.5 with +162 odds). The over/under is 8 runs for this game.

Check out everything you need from a betting perspective on the Reds-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Pirates vs. Reds Highlights | MLB on FOX

Check out the best highlights between the Pittsburgh Pirates and the Cincinnati Reds.

Reds vs. Pirates Game Information & Odds

• When: Saturday, April 12, 2025 at 6:40 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and SportsNet PT

Reds vs. Pirates Prediction

• Score Prediction: Reds 6, Pirates 2
• Total Prediction: Under 8 runs
• Win Probabilities: Reds 75%, Pirates 25%

Reds vs. Pirates Betting Insights

• The Reds have been favorites in four games this season and won two (50%) of those contests.
• Cincinnati has played as favorites of -128 or more twice this season and split those games.
• The oddsmakers' moneyline implies a 56.1% chance of a victory for the Reds.
• The Pirates have won in three of the nine contests they have been named as odds-on underdogs this year.
• This season, Pittsburgh has been victorious one time in six chances when named as an underdog of at least +108 or longer on the moneyline.
• The Pirates have an implied victory probability of 48.1% according to the moneyline set for this matchup.

Reds Recent Betting Performance

• In the last 10 games, the Reds have been named the moneyline favorite by oddsmakers only two times, and they split those games.
• Over their last 10 matchups (all 10 of them had set totals), the Reds and their opponents combined to hit the over three times.
• The Reds' ATS record is 6-4-0 over their past 10 games.

Reds Recent Stats

Reds Player Insights

• De La Cruz is the Reds RBI leader this season, driving in 12 runs to go with his two home runs and .236 batting average.
• In all of MLB, De La Cruz ranks 61st in home runs and 11th in RBI.
• TJ Friedl is batting .250 to pace his team.
• Friedl is 108th in homers in the majors, and 124th in RBI.
• Friedl has two straight games with at least one hit. During his last five outings he is hitting .167 with a double, two walks and two RBI.
• Jose Trevino has a double, a home run and two walks while hitting .280.
• Spencer Steer is batting .132 with two doubles, a home run and four walks.

Reds Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs in eight of their past 10 games and won three of those contests.
• In their last 10 games with a total, the Pirates and their opponents have failed to hit the over five times.
• The Pirates have four wins against the spread in their last 10 chances.

Pirates Recent Stats

Pirates Player Insights

• Hayes is batting .229 with a double, a triple, a home run and seven walks, while getting on base at a rate of .327.
• Among all hitters in the big leagues, Hayes' home run total ranks 108th and his RBI tally is 124th.
• Oneil Cruz has racked up a team-best two home runs.
• Cruz is currently 61st in home runs and 124th in RBI in the major leagues.
• Isiah Kiner-Falefa leads the Pirates' lineup with a .279 batting average.
• Bryan Reynolds leads the Pirates with two long balls and runs batted in, driving in six.

Pirates Team Props

Pirates vs. Reds Highlights | MLB on FOX

Check out the best highlights between the Pittsburgh Pirates and the Cincinnati Reds.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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