Red Sox vs. Orioles Prediction, Odds, Picks - August 25

Trevor Story and Jeremiah Jackson will look to continue their recent offensive production when the Boston Red Sox and Baltimore Orioles play at Oriole Park at Camden Yards on Monday, at 6:35 p.m. ET. The Red Sox are -124 moneyline favorites in this matchup with the Orioles (+104). Boston is favored on the run line (-1.5). The total is 9 runs for the game (with -118 odds to go over and -102 odds to go under).

Check out everything you need from a betting perspective on the Red Sox-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Orioles Game Information & Odds

• When: Monday, August 25, 2025 at 6:35 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MASN and NESN

Red Sox vs. Orioles Prediction

• Score Prediction: Red Sox 5, Orioles 4
• Total Prediction: Under 9 runs
• Win Probabilities: Red Sox 52%, Orioles 48%

Red Sox vs. Orioles Betting Insights

• This season, the Red Sox have been favored 77 times and won 45, or 58.4%, of those games.
• Boston has a record of 28-23 in games when oddsmakers favor them by at least -124 on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Red Sox have a 55.4% chance to win.
• The Orioles have been victorious in 32, or 47.1%, of the 68 contests they have been chosen as underdogs in this season.
• This season, Baltimore has been victorious 25 times in 53 chances when named as an underdog of at least +104 or worse on the moneyline.
• The moneyline set for this matchup implies the Orioles have a 49% chance of coming away with a victory in the contest.

Red Sox Recent Betting Performance

• The Red Sox have a 3-3 record from the six games they were moneyline favorites over their last 10 matchups.
• In their last 10 matchups (all 10 of them had set totals), the Red Sox and their opponents combined to go over the run total five times.
• The Red Sox have a 4-6-0 record against the spread over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Jarren Duran leads the Red Sox in OBP, slugging, and hits, getting on base at a rate of .334 while slugging .442 and squaring up 131 base knocks.
• Duran ranks 141st in home runs and 42nd in RBI among all hitters in the majors.
• Story has a club-best 82 runs batted in and .260 batting average.
• Story is 52nd in home runs and 17th in RBI among all MLB hitters this season.
• Alex Bregman is batting .305 with 24 doubles, 16 home runs and 39 walks.
• Ceddanne Rafaela is hitting .249 with 27 doubles, three triples, 14 home runs and 22 walks.
• Rafaela has recorded at least one hit in two straight games. During his last five outings he is batting .176 with two doubles, a walk and an RBI.

Red Sox Team Props

Orioles Recent Betting Performance

• The Orioles have played as underdogs in seven of their past 10 games and have gone 5-2 in those contests.
• In their last 10 games with a total, the Orioles and their opponents are 6-4-0 when it comes to hitting the over.
• The Orioles have won six of their last 10 games against the spread.

Orioles Recent Stats

Orioles Player Insights

• Gunnar Henderson leads the squad with a batting average of .283, and leads the Orioles in home runs, with 16 and runs batted in with 59.
• Among all hitters in the big leagues, Henderson's home run total is 89th and his RBI tally is 77th.
• Henderson carries a six-game hitting streak into this matchup. In his last 10 games he is hitting .275 with a double, a triple, two home runs, five walks and nine RBIs.
• Jackson Holliday is batting .246 with 17 doubles, two triples, 15 home runs and 37 walks.
• Holliday is 105th overall in homers and 130th in RBI this year.
• Colton Cowser is hitting .216 with 11 doubles, 11 home runs and 16 walks.
• Ryan Mountcastle is batting .259 with 14 doubles, four home runs and 11 walks.

Orioles Team Props

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Check out the best highlights between the Boston Red Sox and New York Yankees.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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