Padres vs. Reds Prediction, Odds, Picks - September 8

The San Diego Padres and Luis Arraez will take on Spencer Steer and the Cincinnati Reds at PETCO Park on Monday, with the first pitch at 9:40 p.m. ET. The Reds are +117 moneyline underdogs in this matchup with the favorite Padres (-138). San Diego (-1.5) is the favorite on the run line. The total for the matchup has been set at 7.5 runs.

Take a look at everything you need from a betting perspective on the Padres-Reds game, regarding the run line, moneyline and total, plus expert picks.

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Mets vs. Reds Highlights | MLB on FOX

Check out the best moments between the New York Mets and the Cincinnati Reds.

Padres vs. Reds Game Information & Odds

• When: Monday, September 8, 2025 at 9:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to watch on TV: SDPA and FDSOH

Padres vs. Reds Prediction

• Score Prediction: Padres 5, Reds 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Padres 54%, Reds 46%

Padres vs. Reds Betting Insights

• The Padres have entered the game as favorites 78 times this season and won 46, or 59%, of those games.
• San Diego has a record of 31-20, a 60.8% win rate, when favored by -138 or more by sportsbooks this season.
• The Padres have a 58% chance to win this game based on the implied probability of the moneyline.
• The Reds have come away with 37 wins in the 77 contests they have been listed as the underdogs in this season.
• Cincinnati has a win-loss record of 14-22 when favored by +117 or worse by bookmakers this year.
• The Reds have an implied victory probability of 46.1% according to the moneyline set by sportsbooks for this matchup.

Padres Recent Betting Performance

• The Padres were the moneyline favorite for eight of their last 10 games, and finished 3-5 in those matchups.
• In their last 10 matchups (all had set totals), the Padres combined with their opponents to hit the over on the run total five times.
• The Padres' ATS record is 4-6-0 over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Fernando Tatis Jr. has 27 doubles, two triples, 20 home runs and 83 walks while batting .262.
• Of all batters in baseball, Tatis ranks 64th in home runs and 94th in RBI.
• Tatis carries a four-game hitting streak into this matchup. In his last five games he is batting .227 with two home runs, two walks and four RBIs.
• Manny Machado has shown off his power as he paces his team with 23 home runs and 84 runs batted in.
• Machado ranks 46th in homers and 25th in RBI among all hitters in the majors.
• Arraez leads the Padres with a .285 batting average.
• Ramon Laureano has hit 23 home runs to pace his team.
• Laureano takes an eight-game streak with at least one hit into this one. In his last 10 outings he is hitting .300 with two doubles, two home runs, two walks and five RBIs.

Padres Team Props

Reds Recent Betting Performance

• The Reds have played as underdogs in five of their past 10 games and won one of those contests.
• In their last 10 games with a total, the Reds and their opponents are 5-4-1 when it comes to hitting the over.
• The Reds are 3-7-0 ATS over their last 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz has put up a team-leading 19 home runs and has driven in 80 runs.
• Among all hitters in MLB, De La Cruz ranks 72nd in home runs and 28th in RBI.
• TJ Friedl is hitting .265 with 20 doubles, two triples, 11 home runs and 70 walks.
• Among all MLB hitters, Friedl is 169th in home runs and 171st in RBI.
• Steer has 20 doubles, two triples, 17 home runs and 45 walks while hitting .239.
• Austin Hays is hitting .263 with 15 doubles, five triples, 14 home runs and 27 walks.

Reds Team Props

Mets vs. Reds Highlights | MLB on FOX

Check out the best moments between the New York Mets and the Cincinnati Reds.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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