Padres vs. Pirates Prediction, Odds, Picks - May 2

The San Diego Padres and Pittsburgh Pirates play on Friday at 6:40 p.m. ET. Luis Arraez and Oneil Cruz have been on a tear as of late for their respective clubs. The Pirates are listed as +124 moneyline underdogs for this matchup against the favorite Padres (-148). San Diego is a 1.5-run favorite (at +115 odds). The contest's over/under is set at 8 runs.

Check out everything you need from a betting perspective on the Padres-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Pirates Game Information & Odds

• When: Friday, May 2, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: Apple TV+

Padres vs. Pirates Prediction

• Score Prediction: Padres 5, Pirates 4
• Total Prediction: Over 8 runs
• Win Probabilities: Padres 55%, Pirates 45%

Padres vs. Pirates Betting Insights

• The Padres have entered the game as favorites 16 times this season and won 12, or 75%, of those games.
• San Diego is undefeated in seven games this season when favored by -148 or more on the moneyline.
• The implied probability of a win from the Padres, based on the moneyline, is 59.7%.
• The Pirates have come away with seven wins in the 20 contests they have been listed as the underdogs in this season.
• This season, Pittsburgh has been victorious four times in 14 chances when named as an underdog of at least +124 or longer on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 44.6% chance of coming away with a victory in the contest.

Padres Recent Betting Performance

• The Padres were the moneyline favorite in four of their last 10 games, and went 1-3 in those matchups.
• In their last 10 matchups, the Padres and their opponents combined to go over the total three times (all 10 games had set totals).
• The Padres are 3-7-0 against the spread over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Fernando Tatis Jr.'s eight long balls and 18 RBI both lead the Padres, in addition to his team-high .345 average.
• Among all hitters in baseball, Tatis' home run total ranks him 14th, and his RBI tally ranks him 35th.
• Manny Machado is hitting .279 with 10 doubles, two home runs and 10 walks.
• Machado ranks 160th in homers and 107th in RBI among all batters in MLB.
• Machado has two straight games with at least one hit. During his last five outings he is hitting .263 with a double and three RBI.
• Arraez is hitting .298 with three doubles, a triple, three home runs and five walks.
• Arraez has at least one base hit in two games in a row. In his last five games he is batting .429 with a triple, a home run, two walks and four RBI.
• Xander Bogaerts is batting .243 with eight doubles, a home run and 13 walks.

Padres Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs in eight of their past 10 games and have gone 4-4 in those contests.
• In their last 10 games with a total, the Pirates and their opponents have failed to hit the over four times.
• The Pirates have a record of 6-4-0 ATS over their last 10 games.

Pirates Recent Stats

Pirates Player Insights

• Cruz leads the Pirates with eight long balls and runs batted in, driving in 17.
• Among all hitters in the big leagues, Cruz's home run total is 14th and his RBI tally is 45th.
• Andrew McCutchen has six doubles, three home runs and 12 walks while batting .264.
• McCutchen ranks 117th among all hitters in the majors in homers, and 128th in RBI.
• Bryan Reynolds has five doubles, four home runs and 11 walks while hitting .238.
• Enmanuel Valdez is hitting .232 with three doubles, two triples, two home runs and 11 walks.

Pirates Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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