Orioles vs. Pirates Prediction, Odds, Picks - September 9

Oneil Cruz and Jeremiah Jackson will hit the field when the Pittsburgh Pirates and Baltimore Orioles meet on Tuesday at Oriole Park at Camden Yards. The Orioles are favored in this one, at -155, while the underdog Pirates have +130 odds to play spoiler. Baltimore is the favorite on the run line (-1.5). The over/under is 8 runs for the game.

Take a look at everything you need from a betting perspective on the Orioles-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Dodgers vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Los Angeles Dodgers and the Baltimore Orioles.

Orioles vs. Pirates Game Information & Odds

• When: Tuesday, September 9, 2025 at 6:35 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MASN and SportsNet PT

Orioles vs. Pirates Prediction

• Score Prediction: Orioles 5, Pirates 4
• Total Prediction: Over 8 runs
• Win Probabilities: Orioles 53%, Pirates 47%

Orioles vs. Pirates Betting Insights

• This season, the Orioles have won 29 out of the 62 games, or 46.8%, in which they've been favored.
• Baltimore has entered 10 games this season favored by -155 or more and is 5-5 in those contests.
• The Orioles have a 60.8% chance to win this game based on the implied probability of the moneyline.
• The Pirates have been underdogs in 102 games this season and have come away with the win 43 times (42.2%) in those contests.
• This season, Pittsburgh has come away with a win 18 times in 49 chances when named as an underdog of at least +130 or worse on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 43.5% chance of walking away with the win.

Orioles Recent Betting Performance

• The Orioles were named the moneyline favorite by bookmakers only one time over the last 10 games, and won that matchup.
• In their last 10 outings, the Orioles and their opponents combined to go over the run total four times (all 10 of the games had set totals).
• The Orioles are 7-3-0 against the spread over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• Gunnar Henderson leads the Orioles in runs batted in (61) and has put up a team-best batting average of .274.
• Henderson ranks 107th in home runs and 96th in RBI among all hitters in the majors.
• Jackson Holliday has shown his power as he paces his team with 17 home runs.
• Including all major league hitters, Holliday is 96th in homers and 135th in RBI.
• Ryan Mountcastle has 18 doubles, five home runs and 14 walks while batting .260.
• Colton Cowser is batting .209 with 12 doubles, 13 home runs and 18 walks.

Orioles Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs in 10 of their past 10 games and won five of those contests.
• In their last 10 games with a total, the Pirates and their opponents have failed to hit the over six times.
• The Pirates have won five of their last 10 games against the spread.

Pirates Recent Stats

Pirates Player Insights

• Bryan Reynolds leads the Pirates with 70 runs batted in while accumulating a team-high batting average of .248.
• Among all hitters in the big leagues, Reynolds is 123rd in homers and 60th in RBI.
• Cruz has launched a team-high 19 home runs.
• Cruz is currently 72nd in homers and 114th in RBI in the big leagues.
• Andrew McCutchen has 22 doubles, 13 home runs and 61 walks while hitting .244.
• Tommy Pham is batting .261 with 17 doubles, a triple, eight home runs and 39 walks.

Pirates Team Props

Dodgers vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Los Angeles Dodgers and the Baltimore Orioles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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