Orioles vs. Astros Prediction, Odds, Picks - June 21

Gunnar Henderson and the Baltimore Orioles will try to take down Jose Altuve and the Houston Astros when the teams meet on Friday at 8:10 PM ET. The Orioles are the favorite in this one, at -153, while the underdog Astros have +130 odds to upset. Baltimore (-1.5) is the favorite on the run line. The over/under is 8.5 runs for this matchup (with -107 odds to hit the over and -113 odds to go under).

Here is everything you need from a betting perspective on the Orioles-Astros game, regarding the run line, moneyline and total, plus expert picks.

Astros vs. White Sox Highlights | MLB on FOX

Check out the best moments between the Houston Astros and the Chicago White Sox on Wednesday, June 19.

Orioles vs. Astros Game Information & Odds

• When: Friday, June 21, 2024 at 8:10 PM ET
• Where: Minute Maid Park in Houston, Texas
• How to Watch on TV: SCHN

Orioles vs. Astros Prediction

• Score Prediction: Orioles 5, Astros 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Orioles 56%, Astros 44%

Orioles vs. Astros Betting Insights

• The Orioles have been favorites in 57 games this season and won 38 (66.7%) of those contests.
• Baltimore has entered 24 games this season favored by -153 or more and is 18-6 in those contests.
• Bookmakers have implied with the moneyline set for this matchup that the Orioles have a 60.5% chance to win.
• The Astros have been chosen as underdogs in 16 games this year and have walked away with the win seven times (43.8%) in those games.
• Houston has been listed as an underdog of +130 or more on two occasions this season and lost both games.
• The Astros have an implied victory probability of 43.5% according to the moneyline set by oddsmakers for this matchup.

Orioles Recent Betting Performance

• The Orioles went 4-2 across the six games they were a moneyline favorite in their last 10 matchups.
• In their last 10 outings (all had set totals), the Orioles combined with their opponents to hit the over on the total four times.
• The Orioles' ATS record is 7-3-0 over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• Henderson's 22 homers in 2024 are the most on the Orioles. He's also knocked in 50 runs while hitting .279.
• Henderson ranks second in homers and 12th in RBI among all batters in baseball.
• Henderson takes a hitting streak of 13 games into this game. In his last 10 outings he is hitting .364 with six doubles, two home runs, four walks and five RBI.
• Adley Rutschman has a club-leading 53 RBI and .293 batting average.
• Rutschman ranks 20th in homers and ninth in RBI on the year.
• Anthony Santander is batting .230 with 13 doubles, a triple, 19 home runs and 23 walks.
• Jordan Westburg has 15 doubles, five triples, 11 home runs and 16 walks while batting .279.

Orioles Team Props

Learn more about this Orioles vs. Astros matchup on Fox Sports.

Astros Recent Betting Performance

• Over the past 10 games, the Astros have been underdogs twice and split those games 1-1.
• In their last 10 games with a total, the Astros and their opponents have failed to hit the over seven times.
• The Astros have five wins against the spread in their last 10 chances.

Astros Recent Stats

Astros Player Insights

• Yordan Alvarez paces the Astros with a team-high batting average of .296.
• Alvarez's home run total places him 17th in MLB, and he is 42nd in RBI.
• Altuve has a club-leading .296 batting average.
• Among all major league hitters, Altuve ranks 42nd in homers and 97th in RBI.
• Alex Bregman has 12 doubles, two triples, nine home runs and 24 walks while batting .247.
• Jeremy Pena has 10 doubles, a triple, five home runs and 12 walks while hitting .274.

Astros Team Props

Astros vs. White Sox Highlights | MLB on FOX

Check out the best moments between the Houston Astros and the Chicago White Sox on Wednesday, June 19.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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