Mariners vs. Astros Prediction, Odds, Picks - May 25

The Seattle Mariners and Houston Astros will play on Sunday at Daikin Park, at 2:10 p.m. ET, with Cal Raleigh and Isaac Paredes -- two hot hitters -- expected to step up at the plate. The Mariners are -138 moneyline favorites in this matchup with the Astros (+116). Seattle is a 1.5-run favorite (at +123 odds). The game's over/under is listed at 8.5 runs.

Check out everything you need from a betting perspective on the Mariners-Astros game, regarding the run line, moneyline and total, plus expert picks.

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Mariners vs. Astros Highlights | MLB on FOX

Check out the best moments between the Seattle Mariners and the Houston Astros.

Mariners vs. Astros Game Information & Odds

• When: Sunday, May 25, 2025 at 2:10 p.m. ET
• Where: Daikin Park in Houston, Texas
• How to watch on TV: SCHN and ROOT Sports NW

Mariners vs. Astros Prediction

• Score Prediction: Astros 4, Mariners 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Mariners 55%, Astros 45%

Mariners vs. Astros Betting Insights

• This season, the Mariners have been favored 31 times and won 17, or 54.8%, of those games.
• Seattle has a record of 12-8, a 60% win rate, when favored by -138 or more by bookmakers this season.
• The implied probability of a win from the Mariners, based on the moneyline, is 58%.
• The Astros have come away with nine wins in the 18 contests they have been listed as the underdogs in this season.
• Houston has a win-loss record of 3-1 when favored by +116 or worse by bookmakers this year.
• Bookmakers have implied with the moneyline set for this matchup that the Astros have a 46.3% chance of pulling out a win.

Mariners Recent Betting Performance

• The Mariners went 2-3 across the five games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Mariners and their opponents combined to go over the run total two times.
• The Mariners are 6-4-0 against the spread over their past 10 games.

Mariners Recent Stats

Mariners Player Insights

• Raleigh paces the Mariners in home runs (17) and runs batted in (35).
• In all of MLB, Raleigh is third in homers and 15th in RBI.
• Julio Rodriguez is hitting .227 with six doubles, two triples, nine home runs and 19 walks.
• Among all major league hitters, Rodriguez ranks 36th in homers and 41st in RBI.
• Jorge Polanco is hitting .285 with six doubles, 10 home runs and nine walks.
• J.P. Crawford is batting .260 to pace his team.

Mariners Team Props

Astros Recent Betting Performance

• In seven games over the last 10 matchups when set as underdogs by sportsbooks, the Astros had a record of 4-3.
• The Astros and their opponents have combined to hit the over three times in their last 10 games with a total.
• Over their last 10 games, the Astros are 6-4-0 against the spread.

Astros Recent Stats

Astros Player Insights

• Paredes leads the Astros in home runs (11) and runs batted in (31).
• Paredes' home run total puts him 21st in MLB, and he ranks 24th in RBI.
• Jeremy Pena has eight doubles, a triple, six home runs and 13 walks while hitting .296.
• Pena ranks 91st among all batters in MLB in homers, and 74th in RBI.
• Jake Meyers paces the Astros with a team-best batting average of .308.
• Jose Altuve has six doubles, six home runs and 15 walks while hitting .253.

Astros Team Props

Mariners vs. Astros Highlights | MLB on FOX

Check out the best moments between the Seattle Mariners and the Houston Astros.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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