How to Watch Twins vs. Cardinals: TV Channel & Live Stream - March 27

Updated Mar. 27, 2025 3:23 p.m. ET

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The Minnesota Twins and St. Louis Cardinals will send Pablo Lopez and Sonny Gray to the mound, respectively, on Opening Day at Busch Stadium. First pitch is at 4:15 p.m. ET.

Take a look at everything you need to watch the Twins vs. Cardinals game.

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MLB Commissioner Rob Manfred joins Colin Cowherd to discuss Shohei Ohtani, Los Angeles Dodgers-New York Yankees, the odds of enforcing a salary cap in baseball and whether he would install the Golden At-Bat. Manfred also dives into how MLB's viewership has gone up with the new installed changes the past season.

Twins vs. Cardinals Game Information & How to Watch

When: Thursday, March 27, 2025 at 4:15 p.m. ET
Where: Busch Stadium in St. Louis, Missouri
TV: Watch on FDSMW, MNNT
Box Score: Fox Sports

Twins vs. Cardinals Prediction

Score Prediction: Cardinals 5, Twins 4
Total Prediction: Over 7.5 runs
Win Probabilities: Twins 56%, Cardinals 44%

Twins vs. Cardinals Head to Head

Date	Favorite	Spread	Total	Favorite Moneyline	Underdog Moneyline	Result
8/25/2024	Twins	-1.5	8.5	-143	+120	3-2 STL
8/24/2024	Twins	-1.5	7.5	-142	+119	6-0 MIN
8/23/2024	Twins	-1.5	8.5	-157	+132	6-1 STL
8/3/2023	Twins	-1.5	8.5	-140	+119	5-3 MIN
8/2/2023	Twins	-1.5	8.5	-126	+107	7-3 STL
8/1/2023	Twins	-1.5	8.5	-132	+112	3-2 MIN

Twins Player Insights

Willi Castro finished last season with a .247 batting average while adding 12 home runs and 60 RBI.
Carlos Correa hit .310 with an OBP of .388 and a slugging percentage of .517.
Ryan Jeffers finished with a .226 average last season, with 21 home runs and 64 RBI.
Byron Buxton hit .279 with an OBP of .335, and a slugging percentage of .524.

Twins Recent & Upcoming Games

Date	Opponent	Score	Pitching Matchup
March 27	@ Cardinals	-	Pablo Lopez vs Sonny Gray
March 29	@ Cardinals	-	TBA vs Erick Fedde
March 30	@ Cardinals	-	TBA vs Andre Pallante
March 31	@ White Sox	-	TBA vs TBA
April 1	@ White Sox	-	TBA vs TBA
April 2	@ White Sox	-	Pablo Lopez vs TBA

Cardinals Player Insights

Brendan Donovan had a batting average of .278 with 163 total hits last season.
Alec Burleson hit 21 home runs with 78 runs batted in last year.
Masyn Winn hit .267 last season with 32 doubles, five triples, 15 home runs and 41 walks.
Nolan Arenado had 23 doubles, 16 home runs and 44 walks while batting .272.

Cardinals Recent & Upcoming Games

Date	Opponent	Score	Pitching Matchup
March 27	Twins	-	Sonny Gray vs Pablo Lopez
March 29	Twins	-	Erick Fedde vs TBA
March 30	Twins	-	Andre Pallante vs TBA
March 31	Angels	-	Miles Mikolas vs TBA
April 1	Angels	-	Matthew Liberatore vs TBA
April 2	Angels	-	Sonny Gray vs TBA