Guardians vs. Twins Prediction, Odds, Picks - August 3

Jose Urena takes the mound for the Minnesota Twins on Sunday at Progressive Field against Jose Ramirez and the Cleveland Guardians. First pitch is at 1:40 p.m. ET. The favored Guardians have -174 moneyline odds against the underdog Twins, who are listed at +144. Cleveland (-1.5) is favored on the run line. An 8.5-run total has been listed in the game.

Here is everything you need to know from a betting perspective on the Guardians-Twins game, regarding the run line, moneyline and total, plus expert picks.

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Twins vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Minnesota Twins and Cleveland Guardians.

Guardians vs. Twins Game Information & Odds

• When: Sunday, August 3, 2025 at 1:40 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and MNNT

Guardians vs. Twins Prediction

• Score Prediction: Guardians 5, Twins 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Guardians 54%, Twins 46%

Guardians vs. Twins Betting Insights

• The Guardians have been favorites in 46 games this season and won 29 (63%) of those contests.
• Cleveland has a record of 6-1 in games when sportsbooks favor them by at least -174 on the moneyline.
• The bookmakers' moneyline implies a 63.5% chance of a victory for the Guardians.
• The Twins have come away with 14 wins in the 38 contests they have been listed as the underdogs in this season.
• Minnesota has a win-loss record of 2-4 when favored by +144 or worse by sportsbooks this year.
• The Twins have an implied victory probability of 41% according to the moneyline set by oddsmakers for this matchup.

Guardians Recent Betting Performance

• The Guardians have a 5-2 record over the seven games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 matchups -- all had a set run total -- the Guardians and their opponents combined to hit the over on the total four times.
• The Guardians' ATS record is 4-6-0 over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Ramirez paces the Guardians with 22 home runs and 59 runs batted in, while accumulating a team-best batting average of .300.
• Ramirez ranks 19th in home runs and 47th in RBI among all hitters in baseball.
• Ramirez carries a four-game hitting streak into this matchup. During his last five outings he is batting .350 with a double, a home run, three walks and three RBIs.
• Steven Kwan is hitting .285 with 20 doubles, a triple, nine home runs and 40 walks.
• Kwan is 156th in home runs and 156th in RBI in the majors.
• Carlos Santana is batting .230 with eight doubles, 11 home runs and 47 walks.
• Santana has at least one base hit in five straight games. During his last five outings he is hitting .350 with a double, a walk and two RBIs.
• Kyle Manzardo is hitting .237 with 13 doubles, two triples, 18 home runs and 32 walks.

Guardians Team Props

Twins Recent Betting Performance

• The Twins have played as underdogs in five of their past 10 games and won one of those contests.
• In their last 10 games with a total, the Twins and their opponents are 5-4-1 when it comes to hitting the over.
• The Twins are 5-5-0 ATS over their last 10 games.

Twins Recent Stats

Twins Player Insights

• Trevor Larnach is hitting .244 with 15 doubles, a triple, 13 home runs and 37 walks, while getting on base at a rate of .317.
• Larnach is 99th in home runs and 108th in RBI among all hitters in the big leagues.
• Ryan Jeffers has 19 doubles, seven home runs and 34 walks while hitting .255.
• Jeffers ranks 201st overall in home runs and 178th in RBI this year.
• Brooks Lee has 10 doubles, 10 home runs and 16 walks while hitting .250.
• Kody Clemens is hitting .215 with seven doubles, three triples, 12 home runs and 18 walks.

Twins Team Props

Twins vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Minnesota Twins and Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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