Cubs vs. Pirates Prediction, Odds, Picks - August 17

The Chicago Cubs and Seiya Suzuki will take the field against the Pittsburgh Pirates and Jack Suwinski on Sunday at 2:20 p.m. ET, at Wrigley Field. The Pirates have been listed as +159 moneyline underdogs in this matchup with the favored Cubs (-191). Chicago is a 1.5-run favorite (at +113 odds). The over/under is 7 runs for this game.

Here's everything you need to know from a betting perspective on the Cubs-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Check out the best moments between the Pittsburgh Pirates and Chicago Cubs.

Cubs vs. Pirates Game Information & Odds

• When: Sunday, August 17, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MARQ and SportsNet PT

Cubs vs. Pirates Prediction

• Score Prediction: Cubs 5, Pirates 4
• Total Prediction: Over 7 runs
• Win Probabilities: Cubs 57%, Pirates 43%

Cubs vs. Pirates Betting Insights

• The Cubs have won 55, or 64%, of the 86 games they've played as favorites this season.
• Chicago has a record of 14-3 in games when sportsbooks favor them by at least -191 on the moneyline.
• The Cubs have a 65.6% chance to win this game based on the implied probability of the moneyline.
• The Pirates have been chosen as underdogs in 86 games this year and have walked away with the win 35 times (40.7%) in those games.
• Pittsburgh has a mark of 7-14 in contests where sportsbooks favor it by +159 or worse on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 38.6% chance of walking away with the win.

Cubs Recent Betting Performance

• The Cubs played as the moneyline favorite in eight of their last 10 games, and they finished 3-5 in those matchups.
• In their last 10 matchups (all had set totals), the Cubs combined with their opponents to hit the over on the total one time.
• The Cubs are 4-6-0 against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is batting .265 with 21 doubles, four triples, 18 home runs and 78 walks.
• In all of Major League Baseball, Tucker ranks 57th in homers and 57th in RBI.
• Pete Crow-Armstrong's 27 home runs pace his team.
• Crow-Armstrong is 11th in homers and 16th in RBI among all hitters in the majors.
• Suzuki paces the Cubs in home runs (27) and runs batted in (86).
• Suzuki has at least one base hit in two games in a row. During his last five outings he is hitting .250 with a double, two walks and two RBIs.
• Nico Hoerner has a club-best .294 batting average.
• Hoerner brings a four-game streak with at least one hit into this one. During his last five outings he is batting .350 with a double and an RBI.

Cubs Team Props

Pirates Recent Betting Performance

• In eight games as underdogs over the last 10 matchups, the Pirates have a record of 2-6.
• When it comes to hitting the over, the Pirates and their opponents are 4-6-0 in their last 10 games with a total.
• The Pirates are 4-6-0 ATS over their last 10 games.

Pirates Recent Stats

Pirates Player Insights

• Bryan Reynolds has put up a team-leading 61 runs batted in.
• In all of the majors, Reynolds ranks 115th in homers and 59th in RBI.
• Andrew McCutchen is hitting .241 with 17 doubles, 11 home runs and 48 walks.
• Among all major league hitters, McCutchen ranks 142nd in home runs and 162nd in RBI.
• Isiah Kiner-Falefa has put up a team-best batting average of .267.
• Tommy Pham is hitting .264 with 12 doubles, a triple, six home runs and 33 walks.

Pirates Team Props

Pirates vs. Cubs Highlights | MLB on FOX

Check out the best moments between the Pittsburgh Pirates and Chicago Cubs.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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