Cubs vs. Orioles Prediction, Odds, Picks - August 1

Kyle Tucker and Jackson Holliday will be among the stars on display when the Chicago Cubs play the Baltimore Orioles on Friday at 2:20 p.m. ET, at Wrigley Field. The Cubs are favored in this one, at -154, while the underdog Orioles have +129 odds to play spoiler. Chicago is the run-line favorite (-1.5). The over/under is 7 runs for the game (with -105 odds to hit the over and -115 odds on the under).

Here is everything you need to know from a betting perspective on the Cubs-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Orioles Game Information & Odds

• When: Friday, August 1, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MARQ and MASN2

Cubs vs. Orioles Prediction

• Score Prediction: Cubs 5, Orioles 3
• Total Prediction: Over 7 runs
• Win Probabilities: Cubs 58%, Orioles 42%

Cubs vs. Orioles Betting Insights

• This season, the Cubs have won 50 out of the 74 games, or 67.6%, in which they've been favored.
• Chicago is 28-9 this season when entering a game favored by -154 or more on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Cubs have a 60.6% chance to win.
• The Orioles have been victorious in 24, or 45.3%, of the 53 contests they have been chosen as underdogs in this season.
• This season, Baltimore has been victorious two times in 12 chances when named as an underdog of at least +129 or longer on the moneyline.
• The moneyline set for this matchup implies the Orioles have a 43.7% chance of walking away with the win.

Cubs Recent Betting Performance

• The Cubs played as the moneyline favorite for seven of their last 10 games, and they went 3-4 in those matchups.
• In their last 10 matchups, the Cubs and their opponents combined to go over the run total eight times (all 10 of the games had set totals).
• The Cubs' record against the spread is 3-7-0 over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Tucker has 21 doubles, four triples, 18 home runs and 74 walks while batting .276.
• Among all batters in baseball, Tucker ranks 40th in home runs and 34th in RBI.
• Pete Crow-Armstrong's 27 home runs are a team-high mark.
• Crow-Armstrong ranks sixth in home runs and eighth in RBI among all hitters in the majors.
• Crow-Armstrong enters this game looking for his third game in a row with a hit. In his last five games he is batting .368 with five doubles, a walk and four RBIs.
• Seiya Suzuki has a team-high 81 runs batted in.
• Nico Hoerner's .291 batting average paces his team.

Cubs Team Props

Orioles Recent Betting Performance

• The Orioles have played as underdogs in five of their past 10 games and have gone 3-2 in those contests.
• In their last 10 games with a total, the Orioles and their opponents have failed to hit the over four times.
• The Orioles are 6-4-0 ATS over their last 10 games.

Orioles Recent Stats

Orioles Player Insights

• Gunnar Henderson paces the Orioles with 43 runs batted in while racking up a team-high batting average of .285.
• Among all hitters in the big leagues, Henderson is 107th in homers and 111th in RBI.
• Henderson has collected a hit in three games in a row. During his last five outings he is hitting .350 with a double, a home run, three walks and five RBIs.
• Holliday been a consistent power bat this season, as he leads his team with 14 home runs and 43 RBI.
• Holliday is 86th in home runs and 111th in RBI among all MLB hitters this season.
• Adley Rutschman is hitting .231 with 12 doubles, a triple, eight home runs and 32 walks.
• Jordan Westburg has nine doubles, a triple, 12 home runs and 11 walks while batting .272.

Orioles Team Props

MLB Top 10 Longest Home Runs in July | MLB on FOX

Check out the top 10 longest home runs in the month of July in MLB.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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