Cardinals vs. Pirates Prediction, Odds, Picks - April 7

Oneil Cruz and the Pittsburgh Pirates face the St. Louis Cardinals on Monday at PNC Park. Matthew Liberatore will start for St. Louis, with first pitch at 6:40 p.m. ET. The Pirates have been listed as -104 moneyline underdogs for this matchup with the favorite Cardinals (-115). St. Louis is the favorite on the run line (-1.5). The matchup's over/under is set at 8 runs.

Check out everything you need to know from a betting perspective on the Cardinals-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Cardinals vs. Pirates Game Information & Odds

• When: Monday, April 7, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and FDSMWX

Cardinals vs. Pirates Prediction

• Score Prediction: Cardinals 7, Pirates 6
• Total Prediction: Over 8 runs
• Win Probabilities: Cardinals 51%, Pirates 49%

Cardinals vs. Pirates Betting Insights

• This season, the Cardinals have been favored three times and won one of those games.
• This season St. Louis has won one of its three games when favored by at least -115 on the moneyline.
• The moneyline for this contest implies a 53.5% chance of a victory for the Cardinals.
• The Pirates have won in one of the six contests they have been named as odds-on underdogs this year.
• Pittsburgh has a win-loss record of 1-5 when favored by -104 or worse by sportsbooks this year.
• The moneyline set for this matchup implies the Pirates have a 51% chance of walking away with the win.

Cardinals Player Insights

• Lars Nootbaar is batting .333 with a double, two home runs and six walks.
• Among all hitters in baseball, Nootbaar's home run total places him 42nd, and his RBI tally puts him 48th.
• Nolan Arenado is batting .343 to lead his team.
• Arenado ranks 81st in homers and 48th in RBI among all major league batters this season.
• Arenado carries a nine-game streak with at least one hit into this matchup. In his last nine games he is batting .343 with three doubles, a home run, six walks and six RBI.
• Brendan Donovan is hitting .333 with two doubles, two home runs and three walks.
• Donovan is on a three-game hitting streak entering this contest. In his last five games he is hitting .350 with two doubles, a home run, two walks and five RBI.
• Victor Scott II has a double, a home run and five walks while hitting .281.

Cardinals Team Props

Pirates Player Insights

• Cruz leads the Pirates with two long balls.
• Among all hitters in MLB, Cruz ranks 42nd in home runs and 99th in RBI.
• Ke'Bryan Hayes is hitting .257 with a double, a triple, a home run and three walks.
• Hayes ranks 81st overall in home runs and 99th in RBI this season.
• Isiah Kiner-Falefa leads the Pirates with a team-high batting average of .323.
• Andrew McCutchen is batting .316 with a double, a home run and three walks.

Pirates Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Pittsburgh Pirates

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