Athletics vs. Red Sox Prediction, Odds, Picks - September 10

Payton Tolle will start for the Boston Red Sox in the final of a three-game series against the Athletics and JJ Bleday on Wednesday at 3:35 p.m. ET. The Red Sox are listed as -104 moneyline underdogs in this matchup against the favored Athletics (-115). The Red Sox are favored on the run line (-1.5). The game's over/under has been set at 10 runs.

Take a look at everything you need to know from a betting perspective on the Athletics-Red Sox game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Athletics Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Athletics.

Athletics vs. Red Sox Game Information & Odds

• When: Wednesday, September 10, 2025 at 3:35 p.m. ET
• Where: Sutter Health Park in West Sacramento, California
• How to watch on TV: NBCS-CA and NESN

Athletics vs. Red Sox Prediction

• Score Prediction: Red Sox 7, Athletics 6
• Total Prediction: Over 10 runs
• Win Probabilities: Athletics 51%, Red Sox 49%

Athletics vs. Red Sox Betting Insights

• The Athletics have entered the game as favorites 35 times this season and won 15, or 42.9%, of those games.
• This season, the Athletics have won 12 of their 28 games, or 42.9%, when favored by at least -115 on the moneyline.
• The implied probability of a win from the Athletics, based on the moneyline, is 53.5%.
• The Red Sox have won in 26, or 50%, of the 52 contests they have been named as odds-on underdogs this year.
• This season, the Red Sox have come away with a win 20 times in 42 chances when named as an underdog of at least -104 or worse on the moneyline.
• The Red Sox have an implied victory probability of 51% according to the moneyline set for this matchup.

Athletics Recent Betting Performance

• In the last 10 games, the Athletics were favored on the moneyline three times, but they lost each matchup.
• In their last 10 outings (all 10 of them had set totals), the Athletics and their opponents combined to hit the over five times.
• The Athletics' record against the spread is 3-7-0 over their past 10 games.

Athletics Recent Stats

Athletics Player Insights

• Brent Rooker has 38 doubles, three triples, 27 home runs and 57 walks while hitting .264.
• Among all hitters in the majors, Rooker ranks 29th in homers and 26th in RBI.
• Tyler Soderstrom has collected 86 runs batted in to pace his team.
• Soderstrom ranks 41st in home runs and 24th in RBI in the major leagues.
• Nick Kurtz has launched a team-high 29 home runs.
• Shea Langeliers' 29 home runs are a team-high mark.

Athletics Team Props

Red Sox Recent Betting Performance

• Over the past 10 games, the Red Sox have been underdogs twice and won both contests.
• In their last 10 games with a total, the Red Sox and their opponents have combined to hit the over five times.
• The Red Sox have six wins against the spread in their last 10 chances.

Red Sox Recent Stats

Red Sox Player Insights

• Jarren Duran has 38 doubles, 12 triples, 14 home runs and 55 walks while hitting .259.
• Duran's home run total puts him 138th in the big leagues, and he is 39th in RBI.
• Trevor Story proven to be a run producer as he paces his team with 24 home runs and 90 RBI, with a team-high .263 batting average.
• Story is 41st in homers and 17th in RBI among all hitters in the big leagues.
• Ceddanne Rafaela has 29 doubles, three triples, 16 home runs and 23 walks while batting .241.
• Alex Bregman is hitting .279 with 26 doubles, 16 home runs and 41 walks.

Red Sox Team Props

Red Sox vs. Athletics Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Athletics.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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