Athletics vs. Pirates Prediction, Odds, Picks - September 19

Bryan Reynolds and the Pittsburgh Pirates take the field on Friday at PNC Park against Luis Severino, who gets the start for the Athletics. First pitch is at 6:40 p.m. ET. The favored Athletics have -114 moneyline odds to win against the underdog Pirates, who are listed at -105. The Athletics are favored on the run line (-1.5). The game's over/under has been listed at 8.5 runs.

Here's everything you need from a betting perspective on the Athletics-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Check out the best moments between the Chicago Cubs and Pittsburgh Pirates.

Athletics vs. Pirates Game Information & Odds

• When: Friday, September 19, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and NBCS-CA

Athletics vs. Pirates Prediction

• Score Prediction: Pirates 5, Athletics 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Athletics 52%, Pirates 48%

Athletics vs. Pirates Betting Insights

• The Athletics have won 16, or 44.4%, of the 36 games they've played as favorites this season.
• The Athletics have a record of 13-16, a 44.8% win rate, when they're favored by -114 or more by bookmakers this season.
• The Athletics have a 53.3% chance to win this game based on the implied probability of the moneyline.
• The Pirates have been victorious in 43, or 40.6%, of the 106 contests they have been chosen as underdogs in this season.
• This year, the Pirates have won 40 of 101 games when listed as at least -105 or better on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 51.2% chance of walking away with the win.

Athletics Recent Betting Performance

• The Athletics were the moneyline favorite in three of their last 10 games, and they went 1-2 in those matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Athletics and their opponents combined to go over the run total two times.
• The Athletics have a 7-3-0 record against the spread over their past 10 games.

Athletics Recent Stats

Athletics Player Insights

• Brent Rooker has 40 doubles, three triples, 30 home runs and 61 walks while hitting .267.
• Rooker ranks 16th in home runs and 27th in RBI among all hitters in the majors.
• Tyler Soderstrom has been productive as he leads his team with 90 RBI.
• Soderstrom ranks 48th in homers and 24th in RBI in the bigs.
• Soderstrom carries a five-game streak with at least one hit into this contest. In his last five games he is hitting .400 with two doubles, a walk and four RBIs.
• Nick Kurtz leads the Athletics with 32 home runs.
• Kurtz has at least one base hit in two straight games. During his last five outings he is hitting .200 with a double, two home runs, two walks and six RBIs.
• Jacob Wilson's .320 batting average paces his team.
• Wilson is riding a five-game hitting streak into this one. In his last five games he is hitting .400 with two doubles, a home run, a walk and three RBIs.

Athletics Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs five times over their past 10 games and lost each of those contests.
• In their last 10 games with a total, the Pirates and their opponents have combined to hit the over three times.
• Over their last 10 games, the Pirates are 3-7-0 against the spread.

Pirates Recent Stats

Pirates Player Insights

• Reynolds leads the Pirates with 71 runs batted in while racking up a team-high batting average of .241.
• Among all hitters in the big leagues, Reynolds is 132nd in home runs and 72nd in RBI.
• Andrew McCutchen is batting .239 with 22 doubles, 13 home runs and 64 walks.
• McCutchen is 155th among all hitters in the big leagues in homers, and 130th in RBI.
• Oneil Cruz has 19 home runs, best in the lineup.
• Spencer Horwitz has 22 doubles, nine home runs and 38 walks while hitting .260.

Pirates Team Props

Cubs vs. Pirates Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and Pittsburgh Pirates.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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