Astros vs. White Sox Prediction, Odds, Picks - May 3

Luis Robert and the Chicago White Sox hit the field on Saturday at Rate Field against Hunter Brown, who gets the start for the Houston Astros. First pitch is set for 2:10 p.m. ET. Oddsmakers list the Astros as -230 favorites on the moneyline, while giving the underdog White Sox +189 moneyline odds to win. Houston is the run-line favorite (-1.5). The over/under is 7.5 runs for the contest (with -113 odds to go over and -107 odds to go under).

Take a look at everything you need from a betting perspective on the Astros-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Astros vs. White Sox Highlights | MLB on FOX

Check out the best moments between the Houston Astros and Chicago White Sox.

Astros vs. White Sox Game Information & Odds

• When: Saturday, May 3, 2025 at 2:10 p.m. ET
• Where: Rate Field in Chicago, Illinois
• How to watch on TV: CHSN and SCHN

Astros vs. White Sox Prediction

• Score Prediction: Astros 5, White Sox 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Astros 52%, White Sox 48%

Astros vs. White Sox Betting Insights

• The Astros have entered the game as favorites 22 times this season and won 11, or 50%, of those games.
• Houston has not entered a game this season as bigger favorites on the moneyline than the -230 odds on them winning this game.
• The sportsbooks' moneyline implies a 69.7% chance of a victory for the Astros.
• The White Sox have won in nine, or 28.1%, of the 32 contests they have been named as odds-on underdogs this year.
• Chicago has a win-loss record of 2-11 when favored by +189 or worse by sportsbooks this year.
• Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 34.6% chance of pulling out a win.

Astros Recent Betting Performance

• The Astros have a 5-4 record across the nine games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 outings (all had set totals), the Astros combined with their opponents to hit the over on the total five times.
• The Astros have put together a 6-4-0 record against the spread over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Jeremy Pena leads the Astros with four home runs while racking up a team-high batting average of .278.
• In all of MLB, Pena is 82nd in home runs and 136th in RBI.
• Pena carries a six-game hitting streak into this matchup. During his last 10 games he is hitting .385 with two doubles, a home run, three walks and five RBI.
• Isaac Paredes has put his power on display as he leads his team with four home runs.
• Paredes ranks 82nd in home runs and 95th in RBI on the year.
• Paredes heads into this game looking for his fifth game in a row with a hit. During his last five outings he is batting .235 with a triple, five walks and an RBI.
• Jose Altuve paces the Astros with four home runs.
• Altuve is on a two-game hitting streak entering this contest. In his last five games he is hitting .211 with a double, a home run, four walks and five RBI.
• Yordan Alvarez has racked up 18 runs batted in to pace his team.

Astros Team Props

White Sox Recent Betting Performance

• The White Sox have played as underdogs in 10 of their past 10 games and have gone 4-6 in those contests.
• In their last 10 games with a total, the White Sox and their opponents are 6-4-0 when it comes to hitting the over.
• The White Sox have a record of 6-4-0 ATS over their last 10 games.

White Sox Recent Stats

White Sox Player Insights

• Robert leads the White Sox in home runs (five) and runs batted in (14).
• Robert's home run total puts him 52nd in the majors, and he is 95th in RBI.
• Robert carries a seven-game hitting streak into this matchup. During his last 10 games he is hitting .270 with two doubles, three home runs, seven walks and eight RBI.
• Miguel Vargas is batting .216 with six doubles, two home runs and 13 walks.
• Among all MLB hitters, Vargas ranks 168th in homers and 136th in RBI.
• Andrew Benintendi has five home runs, tops in the clubhouse.
• Brooks Baldwin has driven in the most runs for the White Sox with 14 runs batted in.

White Sox Team Props

Astros vs. White Sox Highlights | MLB on FOX

Check out the best moments between the Houston Astros and Chicago White Sox.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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