Astros vs. Red Sox Prediction, Odds, Picks - August 1

Jeremy Pena and the Houston Astros take on Alex Bregman and the Boston Red Sox at Fenway Park on Friday, at 7:10 p.m. ET. Bookmakers list the Astros as -125 favorites on the moneyline, while giving the underdog Red Sox +105 moneyline odds to win. Houston is the favorite on the run line (-1.5). The total is 8 runs for the contest.

Check out everything you need to know from a betting perspective on the Astros-Red Sox game, regarding the run line, moneyline and total, plus expert picks.

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Astros vs. Red Sox Game Information & Odds

• When: Friday, August 1, 2025 at 7:10 p.m. ET
• Where: Fenway Park in Boston, Massachusetts
• How to watch on TV: Apple TV+

Astros vs. Red Sox Prediction

• Score Prediction: Red Sox 5, Astros 4
• Total Prediction: Over 8 runs
• Win Probabilities: Astros 57%, Red Sox 43%

Astros vs. Red Sox Betting Insights

• The Astros have won 42, or 55.3%, of the 76 games they've played as favorites this season.
• Houston has entered 52 games this season favored by -125 or more and is 28-24 in those contests.
• The moneyline for this contest implies a 55.6% chance of a victory for the Astros.
• The Red Sox have come away with 18 wins in the 40 contests they have been listed as the underdogs in this season.
• Boston has a mark of 13-13 in contests where oddsmakers favor it by +105 or worse on the moneyline.
• The moneyline set for this matchup implies the Red Sox have a 48.8% chance of walking away with the win.

Astros Recent Betting Performance

• The Astros have a 3-5 record across the eight games they were favored on the moneyline in their last 10 matchups.
• In their last 10 matchups (all had set totals), the Astros combined with their opponents to hit the over on the run total three times.
• The Astros have gone 5-5-0 against the spread over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Jose Altuve is the Astros RBI leader this season, knocking in 57 runs to go with his 18 home runs and .284 batting average.
• Of all hitters in baseball, Altuve is 40th in home runs and 50th in RBI.
• Altuve brings a hitting streak of two games into this matchup. In his last five games he is hitting .350 with a home run, a walk and four RBIs.
• Pena is batting .322 to pace his team.
• Pena ranks 122nd in home runs and 142nd in RBI among all hitters in baseball.
• Yainer Diaz is hitting .252 with 14 doubles, a triple, 15 home runs and 15 walks.
• Diaz is on a two-game hitting streak entering this contest. In his last five games he is batting .400 with two home runs, a walk and four RBIs.
• Jesus Sanchez has 12 doubles, four triples, 10 home runs and 29 walks while hitting .256.

Astros Team Props

Red Sox Recent Betting Performance

• The Red Sox have played as underdogs in five of their past 10 games and won three of those contests.
• In their last 10 games with a total, the Red Sox and their opponents have failed to hit the over six times.
• Over their last 10 games, the Red Sox are 7-3-0 against the spread.

Red Sox Recent Stats

Red Sox Player Insights

• Jarren Duran paces the Red Sox with a .265 batting average.
• Duran ranks 122nd in homers and 39th in RBI among all hitters in the majors.
• Duran has collected a hit in six straight games. During his last 10 outings he is batting .324 with four doubles, two triples, three home runs, six walks and 10 RBIs.
• Ceddanne Rafaela is batting .262 with 21 doubles, three triples, 14 home runs and 17 walks.
• Rafaela ranks 86th overall in home runs and 79th in RBI this season.
• Trevor Story has collected a team-best 65 runs batted in.
• Wilyer Abreu paces the Red Sox with 20 home runs.

Red Sox Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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