Astros vs. Mariners Prediction, Odds, Picks - May 24

The Houston Astros and Seattle Mariners will play on Saturday at Daikin Park, at 4:10 p.m. ET, with Isaac Paredes and Cal Raleigh among those expected to deliver at the plate. The Astros are favored in this one, at -120, while the underdog Mariners have +100 odds to upset. Houston (-1.5) is the favorite on the run line. An 8.5-run over/under is set for this contest.

Here's everything you need to know from a betting perspective on the Astros-Mariners game, regarding the run line, moneyline and total, plus expert picks.

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Mariners vs. Astros Highlights | MLB on FOX

Check out the best highlights between the Seattle Mariners and the Houston Astros.

Astros vs. Mariners Game Information & Odds

• When: Saturday, May 24, 2025 at 4:10 p.m. ET
• Where: Daikin Park in Houston, Texas
• How to watch on TV: SCHN and ROOT Sports NW

Astros vs. Mariners Prediction

• Score Prediction: Astros 4, Mariners 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Astros 54%, Mariners 46%

Astros vs. Mariners Betting Insights

• The Astros have entered the game as favorites 34 times this season and won 18, or 52.9%, of those games.
• Houston has a record of 14-12 in games when oddsmakers favor them by at least -120 on the moneyline.
• The Astros have a 54.5% chance to win this game based on the implied probability of the moneyline.
• The Mariners have been chosen as underdogs in 20 games this year and have walked away with the win 12 times (60%) in those games.
• This season, Seattle has come away with a win 11 times in 17 chances when named as an underdog of at least +100 or worse on the moneyline.
• The Mariners have an implied victory probability of 50% according to the moneyline set by sportsbooks for this matchup.

Astros Recent Betting Performance

• The Astros have a 2-2 record over the four games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 outings, the Astros and their opponents combined to hit the over three times (all 10 of the games had set totals).
• The Astros' ATS record is 5-5-0 over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Paredes paces the Astros with 11 home runs and 31 runs batted in.
• Among all MLB hitters, Paredes is 67th in batting average, 28th in on-base percentage, and 36th in slugging.
• Jeremy Pena is hitting .292 with eight doubles, a triple, six home runs and 13 walks.
• Pena is 88th in home runs and 71st in RBI among all major league hitters this year.
• Jake Meyers paces the Astros with a team-best batting average of .309.
• Meyers is on an eight-game hitting streak entering this contest. During his last 10 outings he is hitting .314 with a double, a home run, three walks and two RBIs.
• Jose Altuve has six doubles, six home runs and 15 walks while batting .253.
• Altuve has recorded at least one hit in two straight games. In his last five games he is hitting .350 with two home runs, a walk and four RBIs.

Astros Team Props

Mariners Recent Betting Performance

• The Mariners have played as underdogs in six of their past 10 games and won five of those contests.
• In their last 10 games with a total, the Mariners and their opponents are 2-8-0 when it comes to hitting the over.
• The Mariners have seven wins against the spread in their last 10 chances.

Mariners Recent Stats

Mariners Player Insights

• Raleigh paces the Mariners in home runs (17) and runs batted in (35).
• In all of the majors, Raleigh is first in homers and 14th in RBI.
• Raleigh has collected a hit in four games in a row. In his last five games he is batting .350 with two doubles, two home runs, two walks and three RBIs.
• Julio Rodriguez is hitting .230 with six doubles, two triples, nine home runs and 18 walks.
• Rodriguez is 36th overall in homers and 35th in RBI this season.
• Jorge Polanco is batting .285 with six doubles, 10 home runs and nine walks.
• J.P. Crawford leads the Mariners with a team-leading batting average of .266.

Mariners Team Props

Mariners vs. Astros Highlights | MLB on FOX

Check out the best highlights between the Seattle Mariners and the Houston Astros.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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