Western Kentucky vs. Jacksonville State Prediction, Odds, Picks - November 29, 2025

Updated Nov. 29, 2025 9:04 a.m. ET

Data Skrive

Oddsmakers project a close game when the Western Kentucky Hilltoppers (8-3) visit the Jacksonville State Gamecocks (7-4) on Saturday, November 29, 2025 in a matchup between CUSA rivals at AmFirst Stadium. Western Kentucky is favored by 2.5 points. The game's point total is set at 55.5.

Facing the LSU Tigers in their last contest, the Hilltoppers lost 13-10. The Gamecocks lost versus the Florida International Panthers in their last game, 27-21.

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Western Kentucky vs. Jacksonville State Game Information & Odds

When: Saturday, November 29, 2025 at 2 p.m. ET
Location: AmFirst Stadium in Jacksonville, Alabama
TV: ESPN+
Live Box Score on FOX Sports

Western Kentucky vs Jacksonville State Betting Information updated as of November 29, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Western Kentucky	-2.5 (-116)	-139	+117	55.5	-111	-109

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Western Kentucky vs. Jacksonville State Prediction

Pick ATS: Jacksonville State (+2.5)
Pick OU: Under (55.5)
Prediction: Jacksonville State 27, Western Kentucky 26

Predictions are made by the Data Skrive betting model.

Learn more about the Western Kentucky Hilltoppers vs. the Jacksonville State Gamecocks game on FOX Sports!

Western Kentucky vs. Jacksonville State Betting Insights

Per the spread and over/under, the implied score for the matchup is Hilltoppers 29, Gamecocks 26.
The Hilltoppers have a 58.2% chance to claim victory in this contest per the moneyline's implied probability. The Gamecocks hold a 46.1% implied probability.
Western Kentucky has compiled a 9-2-0 record against the spread this season.
Jacksonville State has put together a 5-6-0 record against the spread this season.

Western Kentucky vs. Jacksonville State: Head-to-Head

Jacksonville State has a 2-1 record against Western Kentucky in their last three matchups.
The Gamecocks carry a 2-1 record ATS in those games, while the two teams have gone over the total on one occasion.
Over their last three head-to-head contests, Jacksonville State has racked up 89 points, while Western Kentucky has posted 48.

Western Kentucky vs. Jacksonville State: 2025 Stats Comparison

	Western Kentucky	Jacksonville State
Off. Points per Game (Rank)	29.4 (59)	29.5 (57)
Def. Points per Game (Rank)	22.2 (46)	26.1 (74)
Turnovers Allowed (Rank)	16 (87)	11 (21)
Turnovers Forced (Rank)	12 (89)	19 (20)

Western Kentucky 2025 Key Players

Name	Position	Stats
Maverick McIvor	QB	1,863 YDS (67.3%) / 12 TD / 5 INT 28 RUSH YDS / 1 RUSH TD / 4 RUSH YPG
Matthew Henry	WR	45 REC / 719 YDS / 6 TD / 65.4 YPG
La'Vell Wright	RB	344 YDS / 8 TD / 31.3 YPG / 5.2 YPC 10 REC / 88 REC YDS / 1 REC TD / 8.8 REC YPG
Rodney Tisdale Jr.	QB	1,187 YDS (67.3%) / 9 TD / 5 INT 91 RUSH YDS / 1 RUSH TD / 15.2 RUSH YPG
Jaylen Wester	LB	65 TKL / 1 TFL / 0.5 SACK
Jaylen Lewis	DB	44 TKL / 3 TFL / 2 INT / 2 PD
Harper Holloman	DL	26 TKL / 2 TFL / 2 SACK / 1 INT
Dave Herard	DB	36 TKL / 1 TFL

Jacksonville State 2025 Key Players

Name	Position	Stats
Cam Cook	RB	1,451 YDS / 14 TD / 131.9 YPG / 5.8 YPC 24 REC / 232 REC YDS / 0 REC TD / 23.2 REC YPG
Caden Creel	QB	1,041 YDS (60.9%) / 6 TD / 3 INT 830 RUSH YDS / 5 RUSH TD / 75.5 RUSH YPG
Gavin Wimsatt	QB	731 YDS (56.8%) / 4 TD / 2 INT 244 RUSH YDS / 4 RUSH TD / 34.9 RUSH YPG
Deondre Johnson	WR	15 REC / 442 YDS / 5 TD / 40.2 YPG
Trevor Woods	DB	57 TKL / 0 TFL / 1 INT / 1 PD
Walker O'Steen	LB	54 TKL / 3 TFL / 1 SACK / 2 INT
Caleb Nix	DB	37 TKL / 2 TFL / 4 INT / 4 PD
Malcolm Jones	DB	41 TKL / 3 TFL / 2 SACK