Pittsburgh vs. East Carolina Prediction, Odds, Picks - December 27, 2025

Updated Dec. 24, 2025 9:04 p.m. ET

Data Skrive

The East Carolina Pirates hit the field against the Pittsburgh Panthers in the Military Bowl as major, 10.5-point underdogs on December 27, 2025 at 11 a.m. ET on ESPN. A 53-point over/under is set for the contest.

The Panthers lost to the Miami (FL) Hurricanes, 38-7, in their most recent game. The Pirates' last game was against the Florida Atlantic Owls, and they won by a score of 42-3.

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Pittsburgh vs. East Carolina Game Information & Odds

When: Saturday, December 27, 2025 at 11 a.m. ET
Location: Navy-Marine Corps Memorial Stadium in Annapolis, Maryland
TV: ESPN
Streaming: FOX One + ESPN Bundle

Pittsburgh vs East Carolina Betting Information updated as of December 24, 2025, 8:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Pittsburgh	-10.5 (-107)	-369	+291	53	-105	-114

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Pittsburgh vs. East Carolina Prediction

Pick ATS: East Carolina (+10.5)
Pick OU: Over (53)
Prediction: Pittsburgh 31, East Carolina 25

Predictions are made by the Data Skrive betting model.

Learn more about the Pittsburgh Panthers vs. the East Carolina Pirates game on FOX Sports!

Pittsburgh vs. East Carolina Betting Insights

Per the spread and over/under, the implied score for the matchup is Panthers 32, Pirates 21.
The Panthers have a 78.7% chance to claim victory in this meeting based on the moneyline's implied probability. The Pirates have a 25.6% implied probability.
Pittsburgh has compiled an 8-4-0 ATS record so far this year.
East Carolina has won seven games against the spread this season, failing to cover five times.

Pittsburgh vs. East Carolina: 2025 Stats Comparison

	Pittsburgh	East Carolina
Off. Points per Game (Rank)	35.1 (22)	33.5 (30)
Def. Points per Game (Rank)	24.9 (64)	20.3 (23)
Turnovers Allowed (Rank)	18 (91)	13 (36)
Turnovers Forced (Rank)	20 (29)	18 (42)

Pittsburgh 2025 Key Players

Name	Position	Stats
Mason Heintschel	QB	2,101 YDS (63.8%) / 15 TD / 7 INT 97 RUSH YDS / 2 RUSH TD / 12.1 RUSH YPG
Ja'Kyrian Turner	RB	654 YDS / 7 TD / 59.5 YPG / 5.3 YPC 23 REC / 142 REC YDS / 0 REC TD / 12.9 REC YPG
Raphael Williams	WR	47 REC / 684 YDS / 6 TD / 57 YPG
Kenny Johnson	WR	47 REC / 658 YDS / 5 TD / 54.8 YPG
Kyle Louis	LB	77 TKL / 8 TFL / 3 SACK / 2 INT
Rasheem Biles	LB	81 TKL / 7 TFL / 2.5 SACK / 2 INT
Braylan Lovelace	LB	73 TKL / 4 TFL / 2 INT / 2 PD
Kavir Bains-Marquez	DB	55 TKL / 1 TFL / 3 INT / 3 PD

East Carolina 2025 Key Players

Name	Position	Stats
Katin Houser	QB	3,300 YDS (65.9%) / 19 TD / 6 INT 193 RUSH YDS / 9 RUSH TD / 16.1 RUSH YPG
Anthony Smith	WR	60 REC / 897 YDS / 5 TD / 74.8 YPG
London Montgomery	RB	742 YDS / 7 TD / 61.8 YPG / 4.8 YPC
Marlon Gunn Jr.	RB	532 YDS / 6 TD / 44.3 YPG / 5.7 YPC
Ja'Marley Riddle	DB	55 TKL / 3 TFL / 3 INT / 3 PD
Zion Wilson	DL	29 TKL / 7 TFL / 6 SACK
Samuel Dankah	DL	46 TKL / 3 TFL / 1.5 SACK
Teagan Wilk	DB	32 TKL / 1 TFL / 2 INT / 2 PD