Notre Dame vs. Arkansas Prediction, Odds, Picks - September 27, 2025

Updated Sep. 27, 2025 9:04 a.m. ET

Data Skrive

Oddsmakers give the Notre Dame Fighting Irish (1-2) the advantage on Saturday, September 27, 2025 against the Arkansas Razorbacks (2-2). Notre Dame is favored by 4.5 points. The game has a point total of 64.

The Fighting Irish won versus the Purdue Boilermakers in their most recent game, 56-30. Last time out, the Razorbacks fell to the Memphis Tigers, with 32-31 being the final score.

Keep up with college football all season on FOX Sports.

Notre Dame vs. Arkansas Game Information & Odds

When: Saturday, September 27, 2025 at 12 p.m. ET
Location: Donald W. Reynolds Razorback Stadium in Fayetteville, Arkansas
TV: ABC
Live Box Score on FOX Sports

Notre Dame vs Arkansas Betting Information updated as of September 27, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Notre Dame	-4.5 (-106)	-188	+157	64	-112	-108

Notre Dame vs. Arkansas Prediction

Pick ATS: Arkansas (+4.5)
Pick OU: Over (64)
Prediction: Arkansas 39, Notre Dame 33

Predictions are made by the Data Skrive betting model.

Learn more about the Notre Dame Fighting Irish vs. the Arkansas Razorbacks game on FOX Sports!

Notre Dame vs. Arkansas Betting Insights

Based on the spread and over/under, the implied score for the tilt is Fighting Irish 34, Razorbacks 30.
The Fighting Irish have a 65.3% chance to win this game based on the moneyline's implied probability. The Razorbacks hold a 38.9% implied probability.
Notre Dame has a record of 1-2-0 against the spread this season.
Arkansas has a record of 1-3-0 against the spread this year.

Notre Dame vs. Arkansas: 2025 Stats Comparison

	Notre Dame	Arkansas
Off. Points per Game (Rank)	40 (61)	43.5 (12)
Def. Points per Game (Rank)	32.7 (82)	23.5 (76)
Turnovers Allowed (Rank)	4 (50)	6 (96)
Turnovers Forced (Rank)	3 (96)	6 (27)

Notre Dame 2025 Key Players

Name	Position	Stats
Jeremiyah Love	RB	284 YDS / 3 TD / 94.7 YPG / 5.5 YPC 8 REC / 79 REC YDS / 1 REC TD / 39.5 REC YPG
Jadarian Price	RB	187 YDS / 5 TD / 62.3 YPG / 6.9 YPC
CJ Carr	QB	737 YDS (66.2%) / 5 TD / 2 INT 1 RUSH YDS / 1 RUSH TD / 0.3 RUSH YPG
Jordan Faison	WR	12 REC / 155 YDS / 2 TD / 51.7 YPG
Boubacar Traore	DL	11 TKL / 2 TFL / 1 SACK
Jalen Stroman	DB	15 TKL / 0 TFL
Christian Gray	DB	6 TKL / 0 TFL / 1 INT / 1 PD
Kyngstonn Viliamu-Asa	LB	9 TKL / 1 TFL

Arkansas 2025 Key Players

Name	Position	Stats
Taylen Green	QB	1,191 YDS (64.3%) / 12 TD / 4 INT 360 RUSH YDS / 2 RUSH TD / 90 RUSH YPG
Mike Washington	RB	330 YDS / 4 TD / 82.5 YPG / 7.2 YPC 6 REC / 93 REC YDS / 1 REC TD / 23.3 REC YPG
O'Mega Blake	WR	24 REC / 326 YDS / 3 TD / 81.5 YPG
Rohan Jones	TE	5 REC / 197 YDS / 2 TD / 65.7 YPG
Quincy Rhodes Jr.	DL	15 TKL / 7 TFL / 5 SACK
Xavian Sorey Jr.	LB	29 TKL / 1 TFL / 0.5 SACK / 1 INT
Julian Neal	DB	20 TKL / 1 TFL / 2 INT / 2 PD
Stephen Dix Jr.	LB	26 TKL / 0 TFL