Miami (FL) vs. Virginia Tech Prediction, Odds, Picks - November 22, 2025

Updated Nov. 22, 2025 9:04 a.m. ET

Data Skrive

The No. 14 Miami Hurricanes (8-2) are 18.5-point favorites when they visit the Virginia Tech Hokies (3-7) in an ACC matchup on Saturday, November 22, 2025 at Lane Stadium. The game's over/under is set at 49.5.

The Hurricanes won against the North Carolina State Wolfpack in their last game, 41-7. The Hokies lost to the Florida State Seminoles, 34-14, in their most recent contest.

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Miami (FL) vs. Virginia Tech Game Information & Odds

When: Saturday, November 22, 2025 at 12 p.m. ET
Location: Lane Stadium in Blacksburg, Virginia
TV: ESPN
Live Box Score on FOX Sports

Miami (FL) vs Virginia Tech Betting Information updated as of November 22, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Miami (FL)	-18.5 (-105)	-1010	+650	49.5	-108	-118

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Miami (FL) vs. Virginia Tech Prediction

Pick ATS: Miami (FL) (-18.5)
Pick OU: Over (49.5)
Prediction: Miami (FL) 39, Virginia Tech 12

Predictions are made by the Data Skrive betting model.

Learn more about the Miami Hurricanes vs. the Virginia Tech Hokies game on FOX Sports!

Miami (FL) vs. Virginia Tech Betting Insights

Based on the spread and over/under, the implied score for the game is Hurricanes 34, Hokies 16.
The Hurricanes have a 91.0% chance to claim victory in this meeting based on the moneyline's implied probability. The Hokies hold a 13.3% implied probability.
Miami (FL) has put together a 6-4-0 record against the spread this season.
Virginia Tech has covered just twice in 10 matchups with a spread this year.

Miami (FL) vs. Virginia Tech: Head-to-Head

Miami (FL) has a 3-0 record against Virginia Tech in their last three matchups.
The Hokies have a 2-1 record ATS in those games, while the two teams have gone over the total on two occasions.
Over their last three head-to-head contests, Miami (FL) has racked up 96 points, while Virginia Tech has posted 74.

Miami (FL) vs. Virginia Tech: 2025 Stats Comparison

	Miami (FL)	Virginia Tech
Off. Points per Game (Rank)	33.7 (29)	23.3 (104)
Def. Points per Game (Rank)	14.2 (7)	30.1 (103)
Turnovers Allowed (Rank)	10 (25)	12 (54)
Turnovers Forced (Rank)	18 (20)	6 (129)

Miami (FL) 2025 Key Players

Name	Position	Stats
Carson Beck	QB	2,485 YDS (72.9%) / 18 TD / 9 INT 47 RUSH YDS / 1 RUSH TD / 5.2 RUSH YPG
Mark Fletcher	RB	636 YDS / 9 TD / 79.5 YPG / 5.1 YPC 11 REC / 85 REC YDS / 0 REC TD / 10.6 REC YPG
Malachi Toney	WR	59 REC / 698 YDS / 5 TD / 69.8 YPG
CharMar Brown	RB	350 YDS / 5 TD / 35 YPG / 3.9 YPC 15 REC / 106 REC YDS / 1 REC TD / 15.1 REC YPG
Jakobe Thomas	DB	38 TKL / 4 TFL / 3 SACK / 4 INT
Keionte Scott	DB	43 TKL / 6 TFL / 3 SACK / 1 INT
Akheem Mesidor	DL	35 TKL / 6 TFL / 6 SACK
Rueben Bain Jr.	DL	28 TKL / 3 TFL / 3 SACK / 1 INT

Virginia Tech 2025 Key Players

Name	Position	Stats
Kyron Drones	QB	1,717 YDS (58.3%) / 16 TD / 7 INT 578 RUSH YDS / 9 RUSH TD / 57.8 RUSH YPG
Marcellous Hawkins	RB	677 YDS / 1 TD / 67.7 YPG / 6.2 YPC 11 REC / 67 REC YDS / 1 REC TD / 7.4 REC YPG
Ayden Greene	WR	26 REC / 421 YDS / 3 TD / 42.1 YPG
Terion Stewart	RB	438 YDS / 0 TD / 54.8 YPG / 6.2 YPC
Kemari Copeland	DL	33 TKL / 4 TFL / 4.5 SACK / 1 INT
Kaleb Spencer	LB	38 TKL / 4 TFL / 0.5 SACK
Isaiah Cash	DB	29 TKL / 1 TFL / 1 SACK / 1 INT
Jaden Keller	LB	30 TKL / 1 TFL / 0.5 SACK