Kansas vs. Oklahoma State Prediction, Odds, Picks - November 1, 2025

Updated Nov. 1, 2025 3:04 p.m. ET

FOX Sports

The Oklahoma State Cowboys (1-7) are 24.5-point underdogs in a road Big 12 matchup against the Kansas Jayhawks (4-4) on Saturday, November 1, 2025 at David Booth Kansas Memorial Stadium. A total of 55 points has been set for this game.

Facing the Kansas State Wildcats in their last contest, the Jayhawks lost 42-17. Facing the Texas Tech Red Raiders in their last contest, the Cowboys lost 42-0.

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Kansas vs. Oklahoma State Game Information & Odds

When: Saturday, November 1, 2025 at 4 p.m. ET
Location: David Booth Kansas Memorial Stadium in Lawrence, Kansas
TV: ESPN+
Live Box Score on FOX Sports

Kansas vs Oklahoma State Betting Information updated as of November 1, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Kansas	-24.5 (-111)	-3125	+1260	55	-110	-110

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Kansas vs. Oklahoma State Prediction

Pick ATS: Kansas (-24.5)
Pick OU: Over (55)
Prediction: Kansas 41, Oklahoma State 16

Predictions are made by the Data Skrive betting model.

Learn more about the Kansas Jayhawks vs. the Oklahoma State Cowboys game on FOX Sports!

Kansas vs. Oklahoma State Betting Insights

Based on the spread and over/under, the implied score for the game is Jayhawks 40, Cowboys 15.
The Jayhawks have a 96.9% chance to claim victory in this game per the moneyline's implied probability. The Cowboys hold a 7.4% implied probability.
Kansas has put together a 3-5-0 ATS record so far this year.
Oklahoma State has a record of just 1-7-0 against the spread this year.

Kansas vs. Oklahoma State: Head-to-Head

Over their last three meetings, Oklahoma State has totaled two wins against Kansas.
The Cowboys carry a 2-1 record ATS in those games, while the two teams have gone over the point total on two occasions.
Over their last three head-to-head matchups, Oklahoma State has put up 110 points, while Kansas has tallied 72.

Kansas vs. Oklahoma State: 2025 Stats Comparison

	Kansas	Oklahoma State
Off. Points per Game (Rank)	30.5 (48)	14.5 (132)
Def. Points per Game (Rank)	25.9 (86)	38.9 (134)
Turnovers Allowed (Rank)	9 (56)	9 (56)
Turnovers Forced (Rank)	9 (73)	8 (85)

Kansas 2025 Key Players

Name	Position	Stats
Jalon Daniels	QB	1,881 YDS (66.5%) / 18 TD / 3 INT 235 RUSH YDS / 2 RUSH TD / 29.4 RUSH YPG
Emmanuel Henderson Jr.	WR	34 REC / 554 YDS / 4 TD / 69.3 YPG
Leshon Williams	RB	319 YDS / 5 TD / 45.6 YPG / 5.6 YPC 3 REC / 65 REC YDS / 2 REC TD / 16.3 REC YPG
Cam Pickett	WR	30 REC / 349 YDS / 3 TD / 43.6 YPG
Trey Lathan	LB	53 TKL / 4 TFL / 1.5 SACK / 1 INT
Lyrik Rawls	DB	48 TKL / 1 TFL / 1 INT / 1 PD
Bangally Kamara	LB	31 TKL / 7 TFL / 1.5 SACK
Blake Herold	DL	33 TKL / 2 TFL / 1 SACK

Oklahoma State 2025 Key Players

Name	Position	Stats
Rodney Fields Jr.	RB	420 YDS / 1 TD / 70 YPG / 5.5 YPC 19 REC / 215 REC YDS / 1 REC TD / 43 REC YPG
Gavin Freeman	WR	29 REC / 280 YDS / 2 TD / 35 YPG
Zane Flores	QB	696 YDS (55%) / 0 TD / 3 INT 114 RUSH YDS / 1 RUSH TD / 22.8 RUSH YPG
Trent Howland	RB	166 YDS / 2 TD / 27.7 YPG / 4 YPC
Parker Robertson	DB	51 TKL / 5 TFL / 1 INT / 1 PD
Brandon Rawls	LB	50 TKL / 1 TFL / 1.5 SACK
Wendell Gregory	LB	22 TKL / 10 TFL / 3 SACK
Bryan McCoy	LB	48 TKL / 0 TFL