Houston vs. Rice Prediction, Odds, Picks - September 6, 2025

Updated Sep. 6, 2025 3:04 p.m. ET

Data Skrive

The Rice Owls (1-0) are double-digit underdogs (-13.5) on Saturday, September 6, 2025 against the Houston Cougars (1-0). The contest's over/under is 38.5.

The Cougars beat the Stephen F. Austin Lumberjacks, 27-0, in their last game. The Owls beat the Louisiana Ragin' Cajuns, 14-12, in their last contest.

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Houston vs. Rice Game Information & Odds

When: Saturday, September 6, 2025 at 7 p.m. ET
Location: Rice Stadium in Houston, Texas
TV: ESPN+
Live Box Score on FOX Sports

Houston vs Rice Betting Information updated as of September 6, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Houston	-13.5 (-111)	-585	+426	38.5	-112	-108

Houston vs. Rice Prediction

Pick ATS: Rice (+13.5)
Pick OU: Over (38.5)
Prediction: Houston 23, Rice 18

Predictions are made by the Data Skrive betting model.

Learn more about the Houston Cougars vs. the Rice Owls game on FOX Sports!

Houston vs. Rice Betting Insights

Per the spread and over/under, the implied score for the matchup is Cougars 26, Owls 12.
The Cougars have an 85.4% chance to claim victory in this meeting based on the moneyline's implied probability. The Owls have a 19.0% implied probability.
Houston has covered once in one chances against the spread this season.
Rice has won one game against the spread this season.

Houston vs. Rice: Head-to-Head

Houston owns a 3-1 record against Rice in their last four matchups.
In their most recent four meetings, each team has covered two times with those contests eclipsing the total on three occasions.
Over their last four head-to-head contests, Houston has racked up 152 points, while Rice has accumulated 84.

Houston vs. Rice: 2025 Stats Comparison

	Houston	Rice
Off. Points per Game (Rank)	27 (70)	14 (107)
Def. Points per Game (Rank)	0 (1)	12 (49)
Turnovers Allowed (Rank)	0 (1)	0 (1)
Turnovers Forced (Rank)	2 (22)	2 (22)

Houston 2025 Key Players

Name	Position	Stats
Conner Weigman	QB	159 YDS (62.5%) / 3 TD / 0 INT 39 RUSH YDS / 0 RUSH TD / 39 RUSH YPG
J'Marion Burnette	RB	40 YDS / 0 TD / 40 YPG / 4 YPC 1 REC / 39 REC YDS / 1 REC TD / 39 REC YPG
Tanner Koziol	TE	7 REC / 63 YDS / 1 TD / 63 YPG
Amare Thomas	WR	3 REC / 44 YDS / 1 TD / 44 YPG
Brandon Mack	LB	3 TKL / 0 TFL / 1 SACK
Wrook Brown	DB	3 TKL / 1 TFL / 1 SACK
Jalen Garner	LB	6 TKL / 0 TFL
C.J. Douglas	DB	2 TKL / 0 TFL / 1 INT / 1 PD

Rice 2025 Key Players

Name	Position	Stats
Quinton Jackson	RB	119 YDS / 1 TD / 119 YPG / 5.4 YPC
Aaron Turner	WR	2 REC / 3 YDS / 0 TD / 3 YPG
Daelen Alexander	RB	74 YDS / 0 TD / 74 YPG / 4.9 YPC
Drayden Dickmann	WR	3 REC / 44 YDS / 0 TD / 44 YPG
Tony Anyanwu	DL	4 TKL / 0 TFL / 1 SACK
Michael Daley	DL	4 TKL / 1 TFL / 1 SACK
Joseph Mutombo	DL	2 TKL / 1 TFL / 1 SACK
Jack Kane	DB	2 TKL / 0 TFL / 1 INT / 1 PD