Clemson vs. Louisville Prediction, Odds, Picks - November 2, 2024

Updated Nov. 2, 2024 3:05 p.m. ET

Data Skrive

The No. 11 Clemson Tigers (6-1) are heavy, 10.5-point favorites at home at Memorial Stadium (Clemson, SC) against the Louisville Cardinals (5-3) on Saturday, November 2, 2024. Both teams feature strong passing attacks, with the Tigers 18th in passing yards per game, and the Cardinals 10th. The total for this game has been set at 62 points.

In their last action, the Tigers won against the Virginia Cavaliers, 48-31. In their most recent contest, the Cardinals won against the Boston College Eagles, 31-27.

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Clemson vs. Louisville Game Information & Odds

When: Saturday, November 2, 2024 at 7:30 p.m. ET
Location: Memorial Stadium (Clemson, SC) in Berkeley, California
TV: ESPN
Live Box Score on FOX Sports

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Clemson vs Louisville Betting Information updated as of November 2, 2024, 2:49 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Clemson	-10.5 (-108)	-380	+294	62	-109	-111

Clemson vs. Louisville Prediction

Pick ATS: Louisville (+10.5)
Pick OU: Over (62)
Prediction: Clemson 34, Louisville 29

Predictions are made by the Data Skrive betting model.

Learn more about the Clemson Tigers vs. the Louisville Cardinals game on FOX Sports!

Clemson vs. Louisville Betting Insights

Per the spread and over/under, the implied score for the game is Tigers 36, Cardinals 26.
The Tigers have a 79.2% chance to win this game per the moneyline's implied probability. The Cardinals have a 25.4% implied probability.
Clemson has won four games against the spread this season, while failing to cover three times.
Louisville has a record of 2-5-0 against the spread this year.

Clemson vs. Louisville: Head-to-Head

Clemson owns a 2-0 record against Louisville in their last two matchups.
In those contests against Louisville, the Tigers have covered two times while outpacing the total on one occasion.
Louisville has been outpaced by 21 points in its last two tilts against Clemson.

Clemson vs. Louisville: 2024 Stats Comparison

	Clemson	Louisville
Off. Points per Game (Rank)	42.0 (14)	36.6 (15)
Def. Points per Game (Rank)	23.0 (32)	24.6 (73)
Turnovers Allowed (Rank)	4 (2)	9 (47)
Turnovers Forced (Rank)	13 (36)	7 (110)

Clemson 2024 Key Players

Name	Position	Stats
Cade Klubnik	QB	1,836 YDS (66.7%) / 20 TD / 3 INT 227 RUSH YDS / 4 RUSH TD / 32.4 RUSH YPG
Phil Mafah	RB	692 YDS / 6 TD / 98.9 YPG / 6.5 YPC
Antonio Williams	WR	28 REC / 393 YDS / 5 TD / 56.1 YPG
Jake Briningstool	TE	29 REC / 327 YDS / 4 TD / 46.7 YPG
Wade Woodaz	LB	36 TKL / 3 TFL / 2 SACK / 1 INT
T.J. Parker	DL	21 TKL / 5 TFL / 5 SACK
Avieon Terrell	DB	24 TKL / 2 TFL / 1 SACK / 2 INT
Sammy Brown	LB	20 TKL / 7 TFL / 3 SACK

Louisville 2024 Key Players

Name	Position	Stats
Tyler Shough	QB	2,348 YDS (64.3%) / 20 TD / 5 INT
Ja'Corey Brooks	WR	44 REC / 799 YDS / 8 TD / 99.9 YPG
Isaac Brown	RB	649 YDS / 6 TD / 81.1 YPG / 7.5 YPC 23 REC / 132 REC YDS / 1 REC TD / 16.5 REC YPG
Chris Bell	WR	20 REC / 345 YDS / 2 TD / 43.1 YPG
TJ Quinn	LB	33 TKL / 1 TFL / 1 SACK
Stanquan Clark	LB	29 TKL / 2 TFL
Tamarion McDonald	DB	17 TKL / 3 TFL / 2 SACK
Ashton Gillotte	DL	18 TKL / 4 TFL / 2 SACK