Week 1 of the NFL season is officially underway with the brunt of the opening slate taking place on Sunday. The schedule is filled with high-profile matchups and division battles, headlined by Sunday night’s meeting between the Cardinals and Patriots. Here’s how to watch each and every game on Sunday and Monday night (all times EST).
Tampa Bay Buccaneers at Atlanta Falcons. 1 p.m. on FOX (Sunday Ticket channel 709)
Key matchup: Jameis Winston vs. Atlanta’s young defense
The Falcons have re-tooled their defense with an infusion of youth, particularly at linebacker. Atlanta will start two rookies at the position, which Winston should be able to take advantage of over the middle.
Fun fact: The Falcons and Buccaneers have split their last eight meetings; however, the Bucs have won the last two.
Jason Getz-USA TODAY SportsJason Getz
Buffalo Bills at Baltimore Ravens 1 p.m. on CBS (705)
Key matchup: Ravens receivers vs. Ronald Darby and Stephon Gilmore
The Bills, despite being young at the position, boast one of the best cornerback duos in football. The Ravens’ receiving corps could have a difficult time getting open on the outside – especially rookie Breshad Perriman.
Fun fact: Tyrod Taylor plays against his former team for the first time after being Joe Flacco’s backup for four years.
Christopher Hanewinckel-USA TODAChristopher Hanewinckel
Chicago Bears at Houston Texans 1 p.m. on FOX (710)
Key matchup: DeAndre Hopkins vs. Chicago’s depleted secondary
DeAndre Hopkins is one of the five best receivers in the NFL and he’ll be lining up against arguably the league’s worst secondary. To make matters worse, Tracy Porter and Kyle Fuller are both battling injuries and aren’t certain to play Sunday. Hopkins could be in for a huge day.
Fun fact: The Bears have never beaten the Texans in three meetings and have been outscored 68-35.
Getty ImagesScott Halleran
Green Bay Packers at Jacksonville Jaguars 1 p.m. on FOX (711)
Key matchup: Jalen Ramsey vs. the Packers’ receivers
It’s unclear exactly where Ramsey will line up on Sunday, but he’ll undoubtedly be matched up against either Randall Cobb or Jordy Nelson. The rookie doesn’t get an easy draw in his NFL debut so Aaron Rodgers will benefit greatly by testing him early.
Fun fact: Last time these two teams met, Blaine Gabbert threw for 303 yards, while Rodgers had just 186 yards through the air. Jacksonville actually outgained Green Bay 341 to 238 but lost 24-15.
Logan Bowles-USA TODAY SportsLogan Bowles
San Diego Chargers at Kansas City Chiefs 1 p.m. on CBS (706)
Key matchup: Chargers defensive line vs. Chiefs offensive line
The Chargers will be thin up front as Joey Bosa isn’t expected to play while the Chiefs have a great offensive line, led by Mitch Morse at center. The Chargers will need to get pressure on Alex Smith, but that will be difficult with a lackluster line.
Fun fact: The Chiefs and Chargers combined for 13 points in their last meeting – the fewest in 112 games played between the two teams.
Jake Roth-USA TODAY SportsJake Roth
Oakland Raiders at New Orleans Saints 1 p.m. on FOX (712)
Key matchup: Khalil Mack vs. Terron Armstead
Khalil Mack is among the best pure pass rushers in the NFL, while Terron Armstead is emerging as a talented left tackle. If Armstead can limit Mack to one or fewer sacks when he lines up against him, it’ll be a win.
Fun fact: The last time they met, fullback Marcel Reece totaled 193 total yards and recorded seven first downs. It still wasn’t enough, though, as the Raiders got trounced, 38-17.
Getty ImagesJoe Robbins
Cincinnati Bengals at New York Jets 1 p.m. on CBS (707)
Key matchup: A.J. Green vs. Darrelle Revis
This is a marquee matchup that’s going to be fun to watch all game long. Green has a speed and size advantage on Revis, but it’s hard to bet against one of the best corners in the game. Still, Green gets the edge here on the aging Revis.
Fun fact: In 2013, the last meeting between the two teams, former Bengals receiver Marvin Jones caught eight passes for 122 yards and four touchdowns as Cincinnati rolled over a Geno Smith-led Jets team, 49-9. His four scores were one shy of the NFL record.
Getty ImagesSam Greenwood
Cleveland Browns at Philadelphia Eagles 1 p.m. on CBS (708)
Key matchup: Carson Wentz vs. the unspectacular Browns defense
Carson Wentz’s NFL debut couldn’t come against a more favorable team. The Browns’ secondary is thin with Joe Haden, who’s struggled in recent years, as the top cornerback. Wentz has very little experience, but easy passes to start the game should ease him into the spotlight.
Fun fact: Wentz will be the first rookie quarterback in franchise history to start Week 1. He’ll also be the first rookie quarterback in 20 years to start the season opener with fewer than 30 pass attempts.
Bill Streicher-USA TODAY SportsBill Streicher
Minnesota Vikings at Tennessee Titans 1 p.m. on FOX (713)
Key matchup: Tennessee’s “Exotic Smashmouth” vs. Minnesota’s front seven
The Titans are going to run the ball, then run the ball, then run it some more this season. Head coach Mike Mularkey has made the abundantly clear, but it might be tough sledding against the Vikings’ stout front seven, led by Anthony Barr and Everson Griffen.
Fun fact: Adrian Peterson had the same number of rushing yards in 2015 as the entire Titans team had combined (1,485).
Getty ImagesFrederick Breedon
Miami Dolphins at Seattle Seahawks 4:05 p.m. on CBS (714)
Key matchup: Ndamukong Suh vs. Seattle’s interior line
The Seahawks will be down rookie starter Germain Ifedi at guard, which makes life much easier for Ndamukong Suh. Seattle’s O-line wasn’t great to start, but this will be a huge blow to the offense and could impact Russell Wilson’s performance.
Fun fact: Miami has dominated against Seattle in 14 meetings, owning a 10-4 record against the Seahawks. However, in the Dolphins’ only trip to Century Link Field (then-Qwest Field), they lost 24-17.
Dennis Wierzbicki-USA TODAY SporDennis Wierzbicki
New York Giants at Dallas Cowboys 4:25 p.m. on FOX (715)
Key matchup: Odell Beckham Jr. vs. Orlando Scandrick
Odell Beckham Jr. was dominated by the Cowboys last season, catching just nine passes for 79 yards and no touchdowns in two meetings. And that was without Orlando Scandrick. Now, he’ll be matched up against Dallas’ best corner, which could lead to even worse numbers for OBJ.
Fun fact: The Cowboys will start a rookie quarterback and running back in Week 1 for the first time since 1969 when Roger Staubach and Calvin Hill did it. Dak Prescott and Ezekiel Elliott will get the start this time around.
Jim O'Connor-USA TODAY SportsJim O'Connor
Detroit Lions at Indianapolis Colts 4:25 p.m. on FOX (716)
Key matchup: Megatron-less Matthew Stafford vs. Colts secondary
Matthew Stafford will get his first taste of life without Calvin Johnson, and it’ll come against a secondary that is somewhat depleted. Vontae Davis isn’t certain to play, which could lead to open receivers on the outside. Marvin Jones will see his first action in a Lions uniform, as well.
Fun fact: Andrew Luck led the Colts to a comeback victory in 2012 thanks to two touchdowns in the final three minutes, topping the Lions 35-33 in their most recent meeting.
New England Patriots at Arizona Cardinals 8:30 p.m. on NBC
Key matchup: Jimmy Garoppolo vs. Arizona’s swarming defense
How will Jimmy Garoppolo fare in his first career start? Well, that remains to be seen, but on paper, it doesn’t look like it’ll be a walk in the park. The Cardinals boast a top-10 defense and have no trouble getting to the quarterback.
Fun fact: The game will be played at University of Phoenix Stadium. The last time the Patriots played there, Malcolm Butler stole a Super Bowl from the Seahawks with a game-winning interception at the goal line.
Jeremy Brevard-USA TODAY SportsJeremy Brevard
Pittsburgh Steelers at Washington Redskins: Mon. 9/12 at 7:10 p.m. on ESPN
Key matchup: Antonio Brown vs. Josh Norman
Josh Norman isn’t typically one to follow opposing team’s No. 1 receivers, but he may have to against Antonio Brown. To some, this is a matchup between the game’s best receiver and the league’s top cover corner. And there will be no shortage of trash talk, either.
Fun fact: Antonio Brown had nearly as many receiving yards (1,834) as the Redskins’ top three wide receivers combined (1,909) in 2015.
Bob Donnan-USA TODAY SportsBob Donnan
Los Angeles Rams at San Francisco 49ers: Mon. 9/12 at 10:20 p.m. on ESPN
Key matchup: Todd Gurley vs. Navorro Bowman
The Rams are going to feed the ball to Todd Gurley often on Monday night, as they should. The man he’ll be colliding with on several occasions is Navorro Bowman, San Francisco’s middle linebacker. He’s the team’s best defender and if he’s on his game, he can limit Gurley’s production.
Fun fact: The 49ers and Rams were 31st and 32nd respectively in total offense last season.