49ers vs. Eagles Highlights: CMC's 2nd TD Gives Niners Huge Wild Card Road Win

The Philadelphia Eagles' quest for a repeat ended in shocking fashion on Sunday as the reigning Super Bowl champions fell to the upset-minded San Francisco 49ers at home in the wild-card round of the 2025 NFL playoffs. 

FOX's Tom Brady and Kevin Burkhardt were on the call in Philadelphia in a thrilling game that came down to the final few plays. After facing criticism all year, the Jalen Hurts-led offense had a chance to silence the critics against a banged-up yet scrappy Niners defense, but they couldn't get it done. Meanwhile, the Niners were able to pull off the big road win thanks to a clutch performance by Brock Purdy, Christian McCaffrey and their high-powered offense against Philly's bruising, battle-tested D.

Check below for all the highlights from 49ers vs. Eagles in Philadelphia!