The Biggest NFL Upsets in Week 15 - 2025

In Week 15 of the 2025 NFL season, how many underdogs emerged victorious? Below, we provide a comprehensive list of the teams that pulled off an upset last week.

Read more about last week's NFL games on FOX Sports!

NFL Week 15's Biggest Upsets

Chargers 16, Chiefs 13

• Spread: Chiefs -6
• Total: Under (41.5)
• Moneyline: Chiefs -275, Chargers +225

Falcons 29, Buccaneers 28

• Spread: Buccaneers -5.5
• Total: Over (43.5)
• Moneyline: Buccaneers -275, Falcons +225

Vikings 34, Cowboys 26

• Spread: Cowboys -5
• Total: Over (47.5)
• Moneyline: Cowboys -250, Vikings +200

Saints 20, Panthers 17

• Spread: Panthers -2.5
• Total: Under (41.5)
• Moneyline: Panthers -145, Saints +120

Commanders 29, Giants 21

• Spread: Giants -2.5
• Total: Over (45.5)
• Moneyline: Giants -145, Commanders +120

Broncos 34, Packers 26

• Spread: Packers -1
• Total: Over (42.5)
• Moneyline: Packers -120, Broncos +100

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

FOLLOW Follow your favorites to personalize your FOX Sports experience

National Football League