The Biggest NFL Upsets in Week 15 - 2025

In Week 15 of the 2025 NFL season, how many underdogs emerged victorious? Below, we provide a comprehensive list of the teams that pulled off an upset last week.

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NFL Week 15's Biggest Upsets

Chargers 16, Chiefs 13

• Spread: Chiefs -6
• Total: Under (41.5)
• Moneyline: Chiefs -275, Chargers +225

Falcons 29, Buccaneers 28

• Spread: Buccaneers -5.5
• Total: Over (43.5)
• Moneyline: Buccaneers -275, Falcons +225

Vikings 34, Cowboys 26

• Spread: Cowboys -5
• Total: Over (47.5)
• Moneyline: Cowboys -250, Vikings +200

Saints 20, Panthers 17

• Spread: Panthers -2.5
• Total: Under (41.5)
• Moneyline: Panthers -145, Saints +120

Commanders 29, Giants 21

• Spread: Giants -2.5
• Total: Over (45.5)
• Moneyline: Giants -145, Commanders +120

Broncos 34, Packers 26

• Spread: Packers -1
• Total: Over (42.5)
• Moneyline: Packers -120, Broncos +100

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.