Rams vs. Lions 2025 Prediction, Odds, Picks - Dec 14

The Los Angeles Rams (10-3) are favored by six points against the Detroit Lions (8-5) on December 14, 2025, starting at 4:25 p.m. ET, airing on FOX. The expected point total for the matchup is 55.5.

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Rams vs. Lions Odds & Betting Lines

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Rams vs. Lions Prediction & Pick

• Pick ATS: Rams (-6)
  
• Pick OU: Under (55.5)
  
• Prediction: Rams 33 - Lions 17

How to Watch Los Angeles vs. Detroit

• Game date: Sunday, December 14, 2025
• Time: 4:25 p.m. ET
• Venue: SoFi Stadium
• Location: Inglewood, California
• TV: Watch on FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Rams vs. Lions Recent Matchups

• The last four times Detroit and Los Angeles have squared off, the two teams share the same 2-2 record.
• Detroit has been outscored by 16 points in its last four tilts against Los Angeles.

Los Angeles Betting Info

• In 13 Los Angeles games this year, it has nine wins against the spread.
• When playing as at least 6-point favorites this season, the Rams have an ATS record of 4-2.
• Los Angeles games this year have gone over the total in six out of 13 opportunities (46.2%).
• The Rams have a 10-2 record in games they played as moneyline favorite (winning 83.3% of those games).
• The Rams have a 71.4% chance to win this game, based on the implied probability of the moneyline.

Rams Stats

Los Angeles' Key Players

Offense

• Matthew Stafford has 3,354 passing yards (fourth in the NFL), 35 touchdowns (first in the NFL) and four interceptions this year. He has completed 66.7% of his passes, averaging 258.0 yards per game and 7.8 per attempt.
• Kyren Williams' rushing statline this season includes 952 yards (eighth in the NFL) and eight TDs. He is averaging 73.2 yards per game and 4.9 per attempt (ninth in the NFL).
• Williams has 26 receptions on 35 targets for 197 yards. He has three receiving TDs.
• In the passing attack, Puka Nacua, has racked up 1,186 receiving yards (second in the NFL) and six touchdowns after hauling in 93 balls (first in the NFL) on 118 targets. Per game, he's averaging 98.8 yards and 7.8 receptions over 12 games.
• Davante Adams has racked up 718 receiving yards and 14 touchdowns (first in the NFL) with 56 catches on 105 targets. He is averaging 4.3 receptions and 55.2 yards per game.

Defense

• Over on defense, Nathan Landman has 108 tackles, 5.0 TFL, 1.5 sacks, and one interception in 2025. His tackle total leads the Rams.
• Byron Young has 11.0 sacks (fifth in the NFL) as well as 10.0 TFL and 65 tackles.
• Kamren Curl has collected 97 tackles, 2.0 TFL, two sacks, and two interceptions this year. He's second on the Rams in tackles.
• This season, Jared Verse has 45 tackles, 9.0 TFL, and six sacks.

Detroit Betting Info

• Detroit has gone 7-6-0 against the spread this year.
• Games involving Detroit have hit the over on eight occasions this year.
• This season, the Lions have won one out of the four games in which they've been the underdog.
• The moneyline for this contest implies a 32.8% chance of a victory for the Lions.

Lions Stats

Detroit's Key Players

Offense

• Jahmyr Gibbs has rushed for 13 touchdowns this year, and has put up 1,062 total rushing yards (81.7 per game and 5.7 per carry).
• On top of his impact on the ground, Gibbs has caught 58 passes (on 66 targets) for 474 yards (fourth on the Lions), with three receiving touchdowns. He's averaging 36.5 yards per game.
• Jared Goff has 3,334 passing yards (which ranks fifth in the NFL), 26 touchdowns (second in the NFL) and five interceptions. His completion percentage is 70.1% and he averages 256.5 yards per game and 8.1 per attempt.
• Through 13 games played this season, Amon-Ra St. Brown has 81 catches (6.2 receptions per game on nine targets per game) for 976 yards (fifth in the NFL) and nine receiving touchdowns (second in the NFL).
• David Montgomery puts up 46.4 rushing yards per game over 13 games (603 total yards), with seven rushing touchdowns.
• Montgomery has added 21 catches (1.6 per game) for 164 yards (12.6 per game), without a receiving touchdown. He has been on the receiving end of 25 targets.

Defense

• Jack Campbell has 122 tackles, 9.0 TFL, five sacks, and one pass defended in 2025.
• Aidan Hutchinson has 36 tackles, 9.0 TFL, and 8.5 sacks.
• In the 2025 season, Brian Branch has 75 tackles, 5.0 TFL, and 2.5 sacks through 12 games.
• Alex Anzalone has registered 1.5 sacks to go with 3.0 TFL, 79 tackles, and one interception through 13 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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