Chargers vs. Dolphins 2025 Prediction, Odds, Picks - Oct 12

The Los Angeles Chargers (3-2) are considered favorites (-3.5) according to the point spread ahead of their game against the Miami Dolphins (1-4) on October 12, 2025, starting at 1 p.m. ET, airing on CBS. The game has an over/under of 45.5 points.

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Chargers vs. Dolphins Odds & Betting Lines

Chargers vs. Dolphins Prediction & Pick

• Pick ATS: Chargers (-3.5)
  
• Pick OU: Under (45.5)
  
• Prediction: Chargers 26 - Dolphins 19

How to Watch Los Angeles vs. Miami

• Game date: Sunday, October 12, 2025
• Time: 1 p.m. ET
• Venue: Hard Rock Stadium
• Location: Miami Gardens, Florida
• TV: CBS
• Live Boxscore: FOX Sports

Chargers vs. Dolphins Recent Matchups

• In their past four matchups, Miami has a split 2-2 record against Los Angeles.
• In their last four head-to-head matchups, Los Angeles has tallied 104 points versus Miami, while surrendering only 82 points.

Los Angeles Betting Info

• In five Los Angeles games this year, it has three wins against the spread.
• The Chargers have covered the spread once this season (1-1 ATS) when playing as at least 3.5-point favorites.
• Los Angeles' games this year have eclipsed the over/under one time in five opportunities (20%).
• When playing as the moneyline favorite, the Chargers are 2-2 (winning 50% of the time).
• The Chargers have a 67.2% chance to win this game, based on the implied probability of the moneyline.

Chargers Stats

Los Angeles' Key Players

Offense

• Justin Herbert has passed for 1,229 yards (eighth in the NFL), eight touchdowns (ninth in the NFL) and four interceptions this year. He is averaging 245.8 yards per game and 6.9 per attempt, while completing 65.7% of his attempts.
• He has also rushed for 153 yards (second on the Chargers) without scoring a touchdown on the ground, while averaging 30.6 rushing yards per game.
• Quentin Johnston has 26 receptions for 377 yards (eighth in the NFL) and four TDs. In five games, he is averaging 5.2 catches and 75.4 yards per game.
• In the passing attack, Keenan Allen, has totaled 289 receiving yards and three touchdowns after grabbing 29 balls (10th in the NFL) on 44 targets. Per game, he's averaging 57.8 yards and 5.8 receptions over five games.
• Ladd McConkey has 21 receptions for 213 yards and one touchdown. He's been targeted 34 times in the passing game, and averages 4.2 receptions and 42.6 yards in five games played.

Defense

• On the defensive side for the Chargers, Daiyan Henley has racked up 39 tackles, three TFL, two sacks, and one interception in 2025.
• Derwin James has 37 tackles, five TFL, and 1.5 sacks this season.
• Tuli Tuipulotu has collected 17 tackles, six TFL, four sacks, and two passes defended.
• So far this season, Troy Dye has 32 tackles, three TFL, and one sack. He's third on the Chargers in tackles.

Miami Betting Info

• Miami has covered the spread two times this season (2-3-0).
• The Dolphins covered the spread in their only game when underdogs by 3.5 points or more.
• This year, four Miami games have gone over the point total.
• The Dolphins have lost both games they've played as underdogs this season.
• The implied probability of a win by the Dolphins based on the moneyline is 37.0%.

Dolphins Stats

Miami's Key Players

Offense

• Tua Tagovailoa has thrown for 1,008 yards this year, with 10 touchdowns (third in the NFL) and four interceptions. He is completing 70.7% of his attempts while averaging 201.6 yards per game and 6.7 per attempt.
• De'Von Achane has scored one rushing touchdown, while totaling 262 rushing yards (4.4 per attempt and 52.4 per game).
• Achane has also collected 173 receiving yards (34.6 per game) on 25 catches (five per game). He's been targeted 32 times and has caught three touchdown passes.
• Through five games played this season, Jaylen Waddle has 23 catches (4.6 receptions per game on 6.4 targets per game) for 295 yards and three receiving touchdowns.
• Darren Waller has been targeted nine times, resulting in eight catches for 105 yards .

Defense

• In 2025, Tyrel Dodson has put up two sacks to go with four TFL and 46 tackles over five games.
• Jordyn Brooks has 1.5 sacks in addition to his two TFL and 57 tackles over five games.
• Bradley Chubb has four sacks (first on the Dolphins) in addition to his four TFL and 14 tackles.
• Minkah Fitzpatrick has 29 tackles and one interception.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Miami Dolphins

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