49ers vs. Dolphins 2024 Prediction, Odds, Picks - Dec 22

The San Francisco 49ers (6-8) are considered favorites (-1.5) according to the oddsmakers ahead of their game against the Miami Dolphins (6-8) on December 22, 2024, starting at 4:25 p.m. ET, airing on CBS. The predicted point total for the matchup is 44.5.

Keep up with the 2024 NFL season on FOX Sports.

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49ers vs. Dolphins Odds & Betting Lines

49ers vs. Dolphins Prediction & Pick

• Pick ATS: 49ers (-1.5)
  
• Pick OU: Under (44.5)
  
• Prediction: 49ers 23 - Dolphins 21

How to Watch San Francisco vs. Miami

• Game Date: Sunday, December 22, 2024
• Time: 4:25 p.m. ET
• Venue: Hard Rock Stadium
• Location: Miami Gardens, Florida
• TV: CBS
• Live Boxscore: FOX Sports

Read More NFL Predictions For This Week

• Bengals vs. Browns Prediction
• Falcons vs. Giants Prediction
• Lions vs. Bears Prediction
• Colts vs. Titans Prediction
• Cardinals vs. Panthers Prediction
• Eagles vs. Commanders Prediction
• Rams vs. Jets Prediction
• Vikings vs. Seahawks Prediction
• Bills vs. Patriots Prediction
• Raiders vs. Jaguars Prediction
• Buccaneers vs. Cowboys Prediction
• Packers vs. Saints Prediction

49ers vs. Dolphins Recent Matchups

• Over their last five meetings, Miami has put up three wins against San Francisco.
• Miami has been outpaced by 11 points in its last five tilts versus San Francisco.

San Francisco Betting Info

• San Francisco is 5-9-0 against the spread this year.
• When playing as at least 1.5-point favorites this season, the 49ers have an ATS record of 5-7.
• San Francisco games this year have hit the over on seven of 14 set point totals (50%).
• When playing as the moneyline favorite, the 49ers are 6-6, earning a win 50% of the time.
• Based on this matchup's moneyline, the 49ers' implied win probability is 55.6%.

49ers Stats

San Francisco's Key Players

Offense

• Brock Purdy has thrown for 3,174 yards, 15 touchdowns and nine interceptions this year. He averages 244.2 yards per game and 8.4 per attempt, while completing 65% of his attempts.
• He has tacked on 285 rushing yards (21.9 per game) and four touchdowns on the ground.
• George Kittle has 60 catches for 861 yards and eight TDs. In 12 games, he is averaging five catches and 71.8 yards per game.
• In 12 games played, Jauan Jennings is averaging 67.1 yards and 4.9 receptions per game on the way to 805 receiving yards and 59 catches. He's been targeted 87 times, and has six receiving touchdowns.
• Deebo Samuel has 569 receiving yards and one touchdown with 43 catches on 71 targets. He's averaging 3.3 receptions and 43.8 yards per game.

Defense

• On the defensive side, Fred Warner has 106 tackles, three TFL, one sack, and two interceptions in 2024. His tackle total leads the 49ers.
• Nick Bosa has 40 tackles, 10 TFL, seven sacks, and one interception this season.
• Leonard Floyd has put up 39 tackles, eight TFL, and 8.5 sacks this year.
• This season, Deommodore Lenoir has 72 tackles, two TFL, and two interceptions. He's third on the 49ers in tackles.

Miami Betting Info

• Miami has covered the spread five times this year (5-8-1).
• The Dolphins have been underdogs by 1.5 points or more six times this season and have covered the spread twice.
• This season, six Miami games have gone over the point total.
• The Dolphins have won one of the six games they've played as underdogs this season.
• Bookmakers have implied with the moneyline set for this matchup that the Dolphins have a 48.8% chance to win.

Dolphins Stats

Miami's Key Players

Offense

• This year in 14 games, Devon Achane has churned out 641 rushing yards (leading the Dolphins) and scored four rushing touchdowns. He averages 45.8 yards per game and 3.9 per attempt (34th in the NFL).
• Achane's offensive contributions include 70 receptions (five per game) on 78 targets for 509 yards (36.4 per game) and six receiving touchdowns.
• Through 10 games, Tua Tagovailoa has 2,652 passing yards, with 18 touchdowns against seven interceptions and completing 73.7% of his attempts.
• Tyreek Hill has registered 805 receiving yards and five touchdowns on 67 receptions, while being targeted 103 times on the season.
• Jonnu Smith has 740 receiving yards and six touchdowns from 70 receptions after getting 89 targets.

Defense

• So far in 2024, Jordyn Brooks has put up 121 tackles, nine TFL, and two sacks over 14 games.
• Tyrel Dodson's stats include one interception as well as 88 tackles, five TFL, two sacks, and three passes defended.
• Zach Sieler has 41 tackles, 11 TFL, 7.5 sacks, and one interception in the 2024 season.
• Calais Campbell has four sacks (third on the Dolphins) to go with 10 TFL and 43 tackles through 14 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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