2025 NFL Week 3 Predictions, Betting Odds & TV Schedule

The NFL slate in Week 3, which includes the Detroit Lions versus the Baltimore Ravens, is sure to please.

With Week 3 in the NFL upon us, stay on top of the latest betting odds with our preview below.

Check out the full NFL schedule on FOX Sports!

Week 3 Betting Lines & Game Info

Buffalo Bills vs. Miami Dolphins

Odds & Prediction

• Spread: Bills (-11.5)
• Moneyline: Bills -826, Dolphins +563
• Total: 50.5 points
• Prediction: Bills 32, Dolphins 15

How to Watch

• Game Date: Thursday, Sept. 18
• Game Time: 8:15 p.m. ET
• TV Channel: Amazon Prime Video
• Box Score
• Location: Orchard Park, New York

Cleveland Browns vs. Green Bay Packers

Odds & Prediction

• Spread: Packers (-7.5)
• Moneyline: Packers -444, Browns +345
• Total: 41.5 points
• Prediction: Packers 30, Browns 13

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Cleveland, Ohio

Tampa Bay Buccaneers vs. New York Jets

Odds & Prediction

• Spread: Buccaneers (-6.5)
• Moneyline: Buccaneers -328, Jets +261
• Total: 43 points
• Prediction: Buccaneers 32, Jets 15

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Tampa, Florida

New England Patriots vs. Pittsburgh Steelers

Odds & Prediction

• Spread: Steelers (-1)
• Moneyline: Steelers -115, Patriots -104
• Total: 44.5 points
• Prediction: Steelers 25, Patriots 17

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Foxborough, Massachusetts

Carolina Panthers vs. Atlanta Falcons

Odds & Prediction

• Spread: Falcons (-4.5)
• Moneyline: Falcons -235, Panthers +193
• Total: 44 points
• Prediction: Falcons 29, Panthers 21

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Charlotte, North Carolina

Jacksonville Jaguars vs. Houston Texans

Odds & Prediction

• Spread: Jaguars (-1.5)
• Moneyline: Jaguars -124, Texans +105
• Total: 43.5 points
• Prediction: Texans 25, Jaguars 19

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Jacksonville, Florida

Washington Commanders vs. Las Vegas Raiders

Odds & Prediction

• Spread: Commanders (-3)
• Moneyline: Commanders -154, Raiders +129
• Total: 43.5 points
• Prediction: Commanders 32, Raiders 16

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Landover, Maryland

Tennessee Titans vs. Indianapolis Colts

Odds & Prediction

• Spread: Colts (-6)
• Moneyline: Colts -258, Titans +212
• Total: 43.5 points
• Prediction: Colts 25, Titans 21

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Nashville, Tennessee

Philadelphia Eagles vs. Los Angeles Rams

Odds & Prediction

• Spread: Eagles (-3.5)
• Moneyline: Eagles -198, Rams +164
• Total: 45.5 points
• Prediction: Eagles 28, Rams 16

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Philadelphia, Pennsylvania

Minnesota Vikings vs. Cincinnati Bengals

Odds & Prediction

• Spread: Vikings (-3)
• Moneyline: Vikings -166, Bengals +139
• Total: 42.5 points
• Prediction: Vikings 30, Bengals 19

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Minneapolis, Minnesota

Seattle Seahawks vs. New Orleans Saints

Odds & Prediction

• Spread: Seahawks (-7.5)
• Moneyline: Seahawks -394, Saints +305
• Total: 41.5 points
• Prediction: Seahawks 28, Saints 15

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Seattle, Washington

Los Angeles Chargers vs. Denver Broncos

Odds & Prediction

• Spread: Chargers (-2.5)
• Moneyline: Chargers -151, Broncos +127
• Total: 45.5 points
• Prediction: Chargers 22, Broncos 21

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Inglewood, California

Chicago Bears vs. Dallas Cowboys

Odds & Prediction

• Spread: Cowboys (-1.5)
• Moneyline: Cowboys -124, Bears +104
• Total: 50.5 points
• Prediction: Bears 24, Cowboys 20

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Chicago, Illinois

San Francisco 49ers vs. Arizona Cardinals

Odds & Prediction

• Spread: 49ers (-1.5)
• Moneyline: 49ers -126, Cardinals +106
• Total: 44.5 points
• Prediction: Cardinals 25, 49ers 22

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Santa Clara, California

New York Giants vs. Kansas City Chiefs

Odds & Prediction

• Spread: Chiefs (-6)
• Moneyline: Chiefs -316, Giants +253
• Total: 44.5 points
• Prediction: Chiefs 28, Giants 12

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 8:20 p.m. ET
• TV Channel: NBC
• Box Score
• Location: East Rutherford, New Jersey

Baltimore Ravens vs. Detroit Lions

Odds & Prediction

• Spread: Ravens (-4.5)
• Moneyline: Ravens -242, Lions +199
• Total: 54 points
• Prediction: Ravens 27, Lions 26

How to Watch

• Game Date: Monday, Sept. 22
• Game Time: 8:15 p.m. ET
• TV Channel: ABC/ESPN
• Box Score
• Location: Baltimore, Maryland

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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