2025 NFL Week 3 Predictions, Betting Odds & TV Schedule

The NFL slate in Week 3, which includes the Detroit Lions versus the Baltimore Ravens, is sure to please.

With Week 3 in the NFL upon us, stay on top of the latest betting odds with our preview below.

Check out the full NFL schedule on FOX Sports!

Week 3 Betting Lines & Game Info

Buffalo Bills vs. Miami Dolphins

Odds & Prediction

• Spread: Bills (-11.5)
• Moneyline: Bills -826, Dolphins +563
• Total: 50.5 points
• Prediction: Bills 32, Dolphins 15

How to Watch

• Game Date: Thursday, Sept. 18
• Game Time: 8:15 p.m. ET
• TV Channel: Amazon Prime Video
• Box Score
• Location: Orchard Park, New York

Cleveland Browns vs. Green Bay Packers

Odds & Prediction

• Spread: Packers (-7.5)
• Moneyline: Packers -444, Browns +345
• Total: 41.5 points
• Prediction: Packers 30, Browns 13

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Cleveland, Ohio

Tampa Bay Buccaneers vs. New York Jets

Odds & Prediction

• Spread: Buccaneers (-6.5)
• Moneyline: Buccaneers -328, Jets +261
• Total: 43 points
• Prediction: Buccaneers 32, Jets 15

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Tampa, Florida

New England Patriots vs. Pittsburgh Steelers

Odds & Prediction

• Spread: Steelers (-1)
• Moneyline: Steelers -115, Patriots -104
• Total: 44.5 points
• Prediction: Steelers 25, Patriots 17

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Foxborough, Massachusetts

Carolina Panthers vs. Atlanta Falcons

Odds & Prediction

• Spread: Falcons (-4.5)
• Moneyline: Falcons -235, Panthers +193
• Total: 44 points
• Prediction: Falcons 29, Panthers 21

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Charlotte, North Carolina

Jacksonville Jaguars vs. Houston Texans

Odds & Prediction

• Spread: Jaguars (-1.5)
• Moneyline: Jaguars -124, Texans +105
• Total: 43.5 points
• Prediction: Texans 25, Jaguars 19

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Jacksonville, Florida

Washington Commanders vs. Las Vegas Raiders

Odds & Prediction

• Spread: Commanders (-3)
• Moneyline: Commanders -154, Raiders +129
• Total: 43.5 points
• Prediction: Commanders 32, Raiders 16

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Landover, Maryland

Tennessee Titans vs. Indianapolis Colts

Odds & Prediction

• Spread: Colts (-6)
• Moneyline: Colts -258, Titans +212
• Total: 43.5 points
• Prediction: Colts 25, Titans 21

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Nashville, Tennessee

Philadelphia Eagles vs. Los Angeles Rams

Odds & Prediction

• Spread: Eagles (-3.5)
• Moneyline: Eagles -198, Rams +164
• Total: 45.5 points
• Prediction: Eagles 28, Rams 16

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Philadelphia, Pennsylvania

Minnesota Vikings vs. Cincinnati Bengals

Odds & Prediction

• Spread: Vikings (-3)
• Moneyline: Vikings -166, Bengals +139
• Total: 42.5 points
• Prediction: Vikings 30, Bengals 19

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Minneapolis, Minnesota

Seattle Seahawks vs. New Orleans Saints

Odds & Prediction

• Spread: Seahawks (-7.5)
• Moneyline: Seahawks -394, Saints +305
• Total: 41.5 points
• Prediction: Seahawks 28, Saints 15

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Seattle, Washington

Los Angeles Chargers vs. Denver Broncos

Odds & Prediction

• Spread: Chargers (-2.5)
• Moneyline: Chargers -151, Broncos +127
• Total: 45.5 points
• Prediction: Chargers 22, Broncos 21

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:05 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Inglewood, California

Chicago Bears vs. Dallas Cowboys

Odds & Prediction

• Spread: Cowboys (-1.5)
• Moneyline: Cowboys -124, Bears +104
• Total: 50.5 points
• Prediction: Bears 24, Cowboys 20

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Chicago, Illinois

San Francisco 49ers vs. Arizona Cardinals

Odds & Prediction

• Spread: 49ers (-1.5)
• Moneyline: 49ers -126, Cardinals +106
• Total: 44.5 points
• Prediction: Cardinals 25, 49ers 22

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Santa Clara, California

New York Giants vs. Kansas City Chiefs

Odds & Prediction

• Spread: Chiefs (-6)
• Moneyline: Chiefs -316, Giants +253
• Total: 44.5 points
• Prediction: Chiefs 28, Giants 12

How to Watch

• Game Date: Sunday, Sept. 21
• Game Time: 8:20 p.m. ET
• TV Channel: NBC
• Box Score
• Location: East Rutherford, New Jersey

Baltimore Ravens vs. Detroit Lions

Odds & Prediction

• Spread: Ravens (-4.5)
• Moneyline: Ravens -242, Lions +199
• Total: 54 points
• Prediction: Ravens 27, Lions 26

How to Watch

• Game Date: Monday, Sept. 22
• Game Time: 8:15 p.m. ET
• TV Channel: ABC/ESPN
• Box Score
• Location: Baltimore, Maryland

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.