Reds vs. Pirates Prediction, Odds, Picks - April 11

TJ Friedl and the Cincinnati Reds will play Oneil Cruz and the Pittsburgh Pirates at Great American Ball Park in the first of a three-game series, Friday at 6:40 p.m. ET. The Pirates have been listed as +140 moneyline underdogs in this matchup with the favored Reds (-166). Cincinnati (-1.5) is favored on the run line. An 8-run over/under is set in the matchup.

Check out everything you need from a betting perspective on the Reds-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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St. Louis Cardinals vs. Pittsburgh Pirates Highlights | MLB on FOX

Check out the best moments from this matchup between the St. Louis Cardinals and the Pittsburgh Pirates.

Reds vs. Pirates Game Information & Odds

• When: Friday, April 11, 2025 at 6:40 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: Apple TV+

Reds vs. Pirates Prediction

• Score Prediction: Reds 5, Pirates 4
• Total Prediction: Over 8 runs
• Win Probabilities: Reds 59%, Pirates 41%

Reds vs. Pirates Betting Insights

• The Reds have won one of the three games they've played as favorites this season.
• Cincinnati has not entered a game this season as bigger favorites on the moneyline than the -166 odds on them winning this game.
• The moneyline for this contest implies a 62.4% chance of a victory for the Reds.
• The Pirates have come away with three wins in the eight contests they have been listed as the underdogs in this season.
• Pittsburgh has a mark of 1-2 in contests where oddsmakers favor it by +140 or worse on the moneyline.
• The Pirates have an implied victory probability of 41.7% according to the moneyline set for this matchup.

Reds Recent Betting Performance

• The Reds were listed as the moneyline favorite by bookmakers only once over the last 10 games, and lost that matchup.
• In their last 10 matchups, the Reds and their opponents combined to go over the total four times (all 10 games had set totals).
• The Reds have a 6-4-0 record against the spread over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz has put up a team-best batting average of .250 while pacing the Reds in runs batted in (12).
• Of all hitters in baseball, De La Cruz ranks 56th in homers and 10th in RBI.
• Friedl is hitting .245 with a double, a home run and three walks.
• Friedl ranks 103rd in homers and 104th in RBI in the major leagues.
• Jose Trevino has a double, a home run and two walks while hitting .273.
• Santiago Espinal is hitting .233 with a double and two walks.

Reds Team Props

Pirates Recent Betting Performance

• In eight games as underdogs over the last 10 matchups, the Pirates have a record of 3-5.
• In their last 10 games with a total, the Pirates and their opponents are 5-5-0 when it comes to hitting the over.
• The Pirates have a record of 4-6-0 ATS over their last 10 games.

Pirates Recent Stats

Pirates Player Insights

• Cruz has put up a team-high two home runs.
• Cruz's home run total places him 56th in the big leagues, and he is 104th in RBI.
• Ke'Bryan Hayes is batting .239 with a double, a triple, a home run and five walks.
• Hayes ranks 103rd overall in homers and 104th in RBI this year.
• Isiah Kiner-Falefa leads the Pirates with a team-best batting average of .300.
• Bryan Reynolds paces the Pirates in home runs (two) and runs batted in (six).

Pirates Team Props

St. Louis Cardinals vs. Pittsburgh Pirates Highlights | MLB on FOX

Check out the best moments from this matchup between the St. Louis Cardinals and the Pittsburgh Pirates.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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