Reds vs. Cardinals Prediction, Odds, Picks - August 29

TJ Friedl and the Cincinnati Reds hit the field against Nolan Gorman and the St. Louis Cardinals at Great American Ball Park on Friday, at 6:40 p.m. ET. The Reds are the favorite in this one, at -139, while the underdog Cardinals have +117 odds to play spoiler. Cincinnati is favored on the run line (-1.5). The total for the game is set at 9 runs.

Here's everything you need to know from a betting perspective on the Reds-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Pirates vs. Cardinals Highlights | MLB on FOX

Check out the best moments between Pittsburgh Pirates and the St. Louis Cardinals.

Reds vs. Cardinals Game Information & Odds

• When: Friday, August 29, 2025 at 6:40 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and FDSMW

Reds vs. Cardinals Prediction

• Score Prediction: Reds 5, Cardinals 4
• Total Prediction: Under 9 runs
• Win Probabilities: Reds 55%, Cardinals 45%

Reds vs. Cardinals Betting Insights

• The Reds have won 30, or 52.6%, of the 57 games they've played as favorites this season.
• Cincinnati has entered 21 games this season favored by -139 or more and is 11-10 in those contests.
• Bookmakers have implied with the moneyline set for this matchup that the Reds have a 58.2% chance to win.
• The Cardinals have been chosen as underdogs in 72 games this year and have walked away with the win 34 times (47.2%) in those games.
• St. Louis has a mark of 16-23 in contests where bookmakers favor it by +117 or worse on the moneyline.
• The Cardinals have an implied victory probability of 46.1% according to the moneyline set for this matchup.

Reds Recent Betting Performance

• The Reds went 3-1 over the four games they were favored on the moneyline in their last 10 matchups.
• In their last 10 matchups (all 10 of them had set totals), the Reds and their opponents combined to go over the run total three times.
• The Reds' record against the spread is 5-5-0 over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz is the Reds best power hitter, connecting on 19 homers this season in addition to collecting 77 RBI, both team highs.
• Of all batters in baseball, De La Cruz's home run total places him 63rd, and his RBI tally puts him 24th.
• De La Cruz takes a hitting streak of two games into this game. In his last five games he is batting .227 with a double.
• Friedl is hitting .266 with 18 doubles, two triples, 10 home runs and 62 walks.
• Friedl is 178th in home runs and 184th in RBI among all batters in the majors.
• Friedl carries a three-game streak with at least one hit into this matchup. During his last five outings he is batting .238 with two walks and an RBI.
• Spencer Steer is batting .235 with 19 doubles, two triples, 16 home runs and 41 walks.
• Austin Hays has 13 doubles, five triples, 11 home runs and 27 walks while batting .266.

Reds Team Props

Cardinals Recent Betting Performance

• The Cardinals have played as underdogs in five of their past 10 games and have gone 2-3 in those contests.
• In their last 10 games with a total, the Cardinals and their opponents are 6-3-1 when it comes to hitting the over.
• The Cardinals have a record of 4-6-0 ATS over their last 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• Willson Contreras leads the Cardinals with 19 long balls and runs batted in, driving in 73.
• In all of the majors, Contreras ranks 63rd in homers and 38th in RBI.
• Masyn Winn is hitting .254 with 26 doubles, nine home runs and 32 walks.
• Winn is currently 197th in home runs and 150th in RBI in the major leagues.
• Lars Nootbaar has 21 doubles, 13 home runs and 54 walks while hitting .238.
• Ivan Herrera has 11 doubles, 10 home runs and 30 walks while hitting .281.

Cardinals Team Props

Pirates vs. Cardinals Highlights | MLB on FOX

Check out the best moments between Pittsburgh Pirates and the St. Louis Cardinals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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