Red Sox vs. Angels Prediction, Odds, Picks - June 25

Ceddanne Rafaela and the Boston Red Sox will see Yusei Kikuchi at the rubber for the Los Angeles Angels in the final game of a three-game series, Wednesday at 4:07 p.m. ET. Bookmakers list the Red Sox as -168 favorites on the moneyline, while giving the underdog Angels +140 moneyline odds. Boston is a 1.5-run favorite (at +104 odds). The game's over/under is listed at 8 runs.

Check out everything you need from a betting perspective on the Red Sox-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Angels Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Los Angeles Angels.

Red Sox vs. Angels Game Information & Odds

• When: Wednesday, June 25, 2025 at 4:07 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and NESN

Red Sox vs. Angels Prediction

• Score Prediction: Angels 6, Red Sox 5
• Total Prediction: Over 8 runs
• Win Probabilities: Red Sox 51%, Angels 49%

Red Sox vs. Angels Betting Insights

• The Red Sox have been favorites in 49 games this season and won 25 (51%) of those contests.
• Boston has a record of 4-5, a 44.4% win rate, when favored by -168 or more by sportsbooks this season.
• Oddsmakers have implied with the moneyline set for this matchup that the Red Sox have a 62.7% chance to win.
• The Angels have won in 30, or 46.9%, of the 64 contests they have been named as odds-on underdogs this year.
• This season, Los Angeles has come away with a win 11 times in 25 chances when named as an underdog of at least +140 or longer on the moneyline.
• The moneyline set for this matchup implies the Angels have a 41.7% chance of walking away with the win.

Red Sox Recent Betting Performance

• The Red Sox have a 1-2 record from the three games they were favored on the moneyline over their last 10 matchups.
• Over their last 10 matchups, the Red Sox and their opponents combined to hit the over four times (all 10 of the games had set totals).
• The Red Sox have gone 6-4-0 against the spread over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Jarren Duran's .257 average leads the Red Sox this year. His resume also includes five homers and driven in 38 RBI.
• Duran's home runs rank him 199th in MLB, and he is 69th in RBI.
• Duran brings a hitting streak of three games into this matchup. During his last five outings he is batting .250 with two doubles and a walk.
• Rafaela has 13 doubles, two triples, eight home runs and 14 walks while batting .252.
• Rafaela is 120th in homers and 120th in RBI in the major leagues.
• Wilyer Abreu has launched a team-high 13 home runs.
• Abreu is on a two-game hitting streak entering this contest. During his last five outings he is hitting .400 with a double and four RBIs.
• Trevor Story has totaled 39 runs batted in to pace his team.

Red Sox Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in nine of their past 10 games and won five of those contests.
• In their last 10 games with a total, the Angels and their opponents have combined to hit the over four times.
• The Angels have won eight of their last 10 games against the spread.

Angels Recent Stats

Angels Player Insights

• Nolan Schanuel leads the Angels with a .278 batting average.
• Schanuel is 167th in home runs and 120th in RBI among all hitters in MLB.
• Taylor Ward been a consistent power bat this season, as he paces his team with 19 home runs and 53 runs batted in.
• Ward is currently 10th in home runs and 14th in RBI in the big leagues.
• Zach Neto has put up a team-best batting average of .278.
• Jo Adell is hitting .226 with eight doubles, 16 home runs and 17 walks.

Angels Team Props

Red Sox vs. Angels Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Los Angeles Angels.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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