Padres vs. Rockies Prediction, Odds, Picks - September 5

Kyle Freeland will take the mound for the Colorado Rockies in the first of a three-game series against the San Diego Padres and Jake Cronenworth on Friday at 8:40 p.m. ET. The Padres are -220 moneyline favorites for this matchup with the Rockies (+181). San Diego is favored on the run line (-1.5). The game's over/under is set at 10.5 runs.

Here's everything you need to know from a betting perspective on the Padres-Rockies game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Rockies Game Information & Odds

• When: Friday, September 5, 2025 at 8:40 p.m. ET
• Where: Coors Field in Denver, Colorado
• How to watch on TV: COLR and SDPA

Padres vs. Rockies Prediction

• Score Prediction: Padres 6, Rockies 5
• Total Prediction: Over 10.5 runs
• Win Probabilities: Padres 56%, Rockies 44%

Padres vs. Rockies Betting Insights

• The Padres have been favorites in 75 games this season and won 44 (58.7%) of those contests.
• San Diego has a record of 3-3 when favored by -220 or more by sportsbooks this season.
• The oddsmakers' moneyline implies a 68.8% chance of a victory for the Padres.
• The Rockies have been chosen as underdogs in 136 games this year and have walked away with the win 38 times (27.9%) in those games.
• Colorado has a win-loss record of 15-57 when favored by +181 or worse by sportsbooks this year.
• Oddsmakers have implied with the moneyline set for this matchup that the Rockies have a 35.6% chance of pulling out a win.

Padres Recent Betting Performance

• The Padres went 1-4 across the five games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 outings (all had set totals), the Padres combined with their opponents to go over the total seven times.
• The Padres' record against the spread is 2-8-0 over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Fernando Tatis Jr. has 27 doubles, two triples, 19 home runs and 82 walks while hitting .262.
• Tatis' home runs rank him 70th in MLB, and he is 104th in RBI.
• Manny Machado has hit 22 home runs with 81 runs batted in. Both are team-highs.
• Machado ranks 48th in homers and 24th in RBI in the major leagues.
• Machado carries a two-game streak with at least one hit into this matchup. In his last five games he is batting .222 with a home run, two walks and three RBIs.
• Luis Arraez leads the Padres with a .284 batting average.
• Arraez will look to build on his six-game hitting in this game. In his last 10 outings he is batting .250 with a double, a home run, a walk and five RBIs.
• Ramon Laureano's 22 home runs lead his team.
• Laureano has recorded at least one hit in five games in a row. In his last five games he is hitting .421 with a home run, two walks and four RBIs.

Padres Team Props

Rockies Recent Betting Performance

• The Rockies have played as underdogs in 10 of their past 10 games and won two of those contests.
• In their last 10 games with a total, the Rockies and their opponents have failed to hit the over seven times.
• The Rockies are 4-6-0 ATS over their last 10 games.

Rockies Recent Stats

Rockies Player Insights

• Hunter Goodman leads the lineup with a batting average of .280, and leads the Rockies in home runs, with 27 and runs batted in with 83.
• Among all hitters in the big leagues, Goodman is 24th in home runs and 22nd in RBI.
• Mickey Moniak is hitting .262 with 17 doubles, eight triples, 18 home runs and 19 walks.
• Among all major league hitters, Moniak is 81st in home runs and 111th in RBI.
• Jordan Beck has 25 doubles, five triples, 14 home runs and 39 walks while batting .270.
• Brenton Doyle has 19 doubles, two triples, 14 home runs and 29 walks while hitting .247.

Rockies Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Colorado Rockies

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