Orioles vs. Red Sox Prediction, Odds, Picks - April 3

Ryan O'Hearn and the Baltimore Orioles will play Alex Bregman and the Boston Red Sox on Thursday at Oriole Park at Camden Yards, at 1:05 p.m. ET. Oddsmakers list the Orioles as -127 moneyline favorites, while giving the underdog Red Sox +107 moneyline odds. Baltimore is a 1.5-run favorite (at +157 odds). The total is 9.5 runs for the matchup.

Here's everything you need from a betting perspective on the Orioles-Red Sox game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Baltimore Orioles.

Orioles vs. Red Sox Game Information & Odds

• When: Thursday, April 3, 2025 at 1:05 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MASN and NESN

Orioles vs. Red Sox Prediction

• Score Prediction: Orioles 7, Red Sox 6
• Total Prediction: Over 9.5 runs
• Win Probabilities: Orioles 53%, Red Sox 47%

Orioles vs. Red Sox Betting Insights

• The Orioles won the only game they've played as the favorite this season.
• Baltimore has played as favorites of -127 or more once this season and won that game.
• The oddsmakers' moneyline implies a 55.9% chance of a victory for the Orioles.
• The Red Sox have been underdogs in three games this season, however, they have failed to come away with a win in any of those games.
• Boston has been listed as an underdog of +107 or more on two occasions this season and lost both games.
• The Red Sox have an implied victory probability of 48.3% according to the moneyline set for this matchup.

Orioles Player Insights

• The Orioles RBI leader this season is Cedric Mullins, who has driven in 10 runs while hitting .304 with two home runs.
• Among all hitters in baseball, Mullins is 20th in homers and fifth in RBI.
• Jordan Westburg's three home runs pace his team.
• Westburg is eighth in homers in the majors, and 71st in RBI.
• Westburg heads into this game looking for his fourth game in a row with a hit. During his last five outings he is hitting .381 with three home runs, two walks and three RBI.
• Adley Rutschman is hitting .250 with a double, two home runs and three walks.
• Tyler O'Neill is hitting .444 to pace his team.

Orioles Team Props

Red Sox Player Insights

• Wilyer Abreu paces the Red Sox with two home runs and six runs batted in, while recording a team-best batting average of .500.
• Abreu ranks 20th in homers and 22nd in RBI among all hitters in MLB.
• Kristian Campbell is batting .400 with four doubles, a home run and four walks.
• Campbell is 53rd in home runs and 121st in RBI among all hitters in the big leagues.
• Jarren Duran is batting .231 with a double, a triple and a walk.
• Trevor Story is batting .263 with a home run and a walk.

Red Sox Team Props

Red Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Baltimore Orioles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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