Marlins vs. Nationals Prediction, Odds, Picks - September 10

A couple of hot hitters, Otto Lopez and C.J. Abrams, will be on display when the Miami Marlins play the Washington Nationals on Wednesday at 6:40 p.m. ET, at loanDepot park. The favored Marlins have -156 moneyline odds against the underdog Nationals, who are listed at +130. Miami (-1.5) is favored on the run line. The over/under is 8.5 runs for the game.

Check out everything you need from a betting perspective on the Marlins-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Nationals vs. Marlins Highlights | MLB on FOX

Check out the best moments between Washington Nationals and the Miami Marlins.

Marlins vs. Nationals Game Information & Odds

• When: Wednesday, September 10, 2025 at 6:40 p.m. ET
• Where: loanDepot park in Miami, Florida
• How to watch on TV: FDSFL and MASN2

Marlins vs. Nationals Prediction

• Score Prediction: Marlins 6, Nationals 5
• Total Prediction: Over 8.5 runs
• Win Probabilities: Marlins 54%, Nationals 46%

Marlins vs. Nationals Betting Insights

• This season, the Marlins have been favored 25 times and won 10, or 40%, of those games.
• Miami has played as favorites of -156 or more twice this season and lost both games.
• The implied probability of a win from the Marlins, based on the moneyline, is 60.9%.
• The Nationals have come away with 54 wins in the 125 contests they have been listed as the underdogs in this season.
• This season, Washington has come away with a win 28 times in 72 chances when named as an underdog of at least +130 or longer on the moneyline.
• The Nationals have an implied victory probability of 43.5% according to the moneyline set by oddsmakers for this matchup.

Marlins Recent Betting Performance

• The Marlins did not win a game while favored on the moneyline over the last 10 games in three tries.
• Over their last 10 matchups (all had set totals), the Marlins combined with their opponents to hit the over on the run total five times.
• The Marlins have gone 3-7-0 against the spread over their past 10 games.

Marlins Recent Stats

Marlins Player Insights

• Lopez is batting .249 with 18 doubles, 14 home runs and 44 walks.
• Of all hitters in baseball, Lopez ranks 138th in home runs and 63rd in RBI.
• Lopez has collected a hit in three straight games. In his last five games he is hitting .353 with two home runs and four RBIs.
• Xavier Edwards is hitting .279 with 20 doubles, five triples, two home runs and 45 walks.
• Edwards ranks 390th in home runs and 224th in RBI among all batters in MLB.
• Edwards has two games in a row with at least one hit. In his last five games he is batting .143 with three walks and two RBIs.
• Agustin Ramirez is hitting .226 with 28 doubles, a triple, 19 home runs and 31 walks.
• Eric Wagaman has 25 doubles, three triples, nine home runs and 32 walks while hitting .238.

Marlins Team Props

Nationals Recent Betting Performance

• The Nationals have played as underdogs in eight of their past 10 games and won five of those contests.
• In their last 10 games with a total, the Nationals and their opponents have failed to hit the over four times.
• The Nationals have seven wins against the spread in their last 10 chances.

Nationals Recent Stats

Nationals Player Insights

• Abrams leads the Nationals with a .268 batting average.
• Abrams' home run total puts him 96th in the majors, and he ranks 135th in RBI.
• Abrams brings a hitting streak of six games into this game. During his last 10 outings he is hitting .289 with six doubles and three walks.
• James Wood been a consistent power bat this season, as he leads his team with 27 home runs and 88 RBI.
• Wood is 29th among all hitters in MLB in home runs, and 21st in RBI.
• Luis Garcia is batting .260 with 27 doubles, a triple, 13 home runs and 26 walks.
• Josh Bell has 13 doubles, a triple, 20 home runs and 54 walks while hitting .232.

Nationals Team Props

Nationals vs. Marlins Highlights | MLB on FOX

Check out the best moments between Washington Nationals and the Miami Marlins.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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