Guardians vs. Rangers Prediction, Odds, Picks - September 26

Josh Jung and the Texas Rangers hit the field on Friday at Progressive Field against Slade Cecconi, who will start for the Cleveland Guardians. First pitch is at 7:10 p.m. ET. The Guardians are -158 moneyline favorites for this matchup against the Rangers (+132). Cleveland is the favorite on the run line (-1.5 with +139 odds). The game's total has been set at 7.5 runs.

Check out everything you need to know from a betting perspective on the Guardians-Rangers game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. Rangers Game Information & Odds

• When: Friday, September 26, 2025 at 7:10 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: MLB Network, CLEG, and Victory+

Guardians vs. Rangers Prediction

• Score Prediction: Guardians 5, Rangers 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Guardians 52%, Rangers 48%

Guardians vs. Rangers Betting Insights

• The Guardians have been favorites in 69 games this season and won 43 (62.3%) of those contests.
• Cleveland is 10-4 this season when entering a game favored by -158 or more on the moneyline.
• The Guardians have a 61.2% chance to win this game based on the implied probability of the moneyline.
• The Rangers have been victorious in 30, or 39.5%, of the 76 contests they have been chosen as underdogs in this season.
• This season, Texas has come away with a win two times in 13 chances when named as an underdog of at least +132 or worse on the moneyline.
• The Rangers have an implied victory probability of 43.1% according to the moneyline set by oddsmakers for this matchup.

Guardians Recent Betting Performance

• The Guardians have a 3-2 record from the five games they were moneyline favorites over their last 10 matchups.
• Over their last 10 matchups, the Guardians and their opponents combined to go over the run total two times (all 10 of the games had set totals).
• The Guardians have an 8-2-0 record against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez leads the Guardians in home runs (30), runs batted in (85) and has accumulated a team-best batting average of .284.
• Of all hitters in baseball, Ramirez is 25th in home runs and 34th in RBI.
• Ramirez carries an eight-game hitting streak into this matchup. In his last 10 games he is batting .333 with five doubles, two home runs, seven walks and eight RBIs.
• Steven Kwan is hitting .275 with 29 doubles, a triple, 11 home runs and 54 walks.
• Kwan is 187th in home runs in baseball, and 138th in RBI.
• Kyle Manzardo is hitting .232 with 18 doubles, two triples, 26 home runs and 48 walks.
• Angel Martinez is batting .226 with 23 doubles, two triples, 11 home runs and 22 walks.

Guardians Team Props

Rangers Recent Betting Performance

• Over the past 10 games, the Rangers have been underdogs twice and lost both contests.
• In their last 10 games with a total, the Rangers and their opponents have failed to hit the over seven times.
• The Rangers have won one of their last 10 games against the spread.

Rangers Recent Stats

Rangers Player Insights

• Josh Smith leads the Rangers with a team-high batting average of .251.
• Among all hitters in the majors, Smith is 211th in home runs and 244th in RBI.
• Adolis Garcia has driven in the most runs for the Rangers with 74 runs batted in.
• Garcia ranks 103rd overall in home runs and 68th in RBI this year.
• Jung is batting .249 with 21 doubles, a triple, 14 home runs and 26 walks.
• Jake Burger is hitting .236 with 15 doubles, a triple, 16 home runs and 12 walks.

Rangers Team Props

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Cleveland Guardians

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