Dodgers vs. Diamondbacks Prediction, Odds, Picks - September 24

The Los Angeles Dodgers and Teoscar Hernandez will take on the Arizona Diamondbacks and Geraldo Perdomo on Wednesday at 9:40 p.m. ET, in the second game of a three-game series at Chase Field. Bookmakers list the Dodgers as -155 moneyline favorites, while giving the underdog Diamondbacks +130 moneyline odds to win. Los Angeles is the run-line favorite (-1.5). The over/under is 8.5 runs for this contest.

Check out everything you need to know from a betting perspective on the Dodgers-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.

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Dodgers vs. Diamondbacks Game Information & Odds

• When: Wednesday, September 24, 2025 at 9:40 p.m. ET
• Where: Chase Field in Phoenix, Arizona
• How to watch on TV: ARID and SportsNet LA

Dodgers vs. Diamondbacks Prediction

• Score Prediction: Diamondbacks 6, Dodgers 5
• Total Prediction: Over 8.5 runs
• Win Probabilities: Dodgers 51%, Diamondbacks 49%

Dodgers vs. Diamondbacks Betting Insights

• The Dodgers have been favorites in 139 games this season and won 79 (56.8%) of those contests.
• Los Angeles is 55-41 this season when entering a game favored by -155 or more on the moneyline.
• The Dodgers have a 60.8% chance to win this game based on the implied probability of the moneyline.
• The Diamondbacks have been underdogs in 67 games this season and have come away with the win 34 times (50.7%) in those contests.
• This season, Arizona has come away with a win 12 times in 20 chances when named as an underdog of at least +130 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Diamondbacks have a 43.5% chance of pulling out a win.

Dodgers Recent Betting Performance

• The Dodgers were the moneyline favorite for nine of their last 10 games, and they went 5-4 in those matchups.
• Over their last 10 matchups, the Dodgers and their opponents combined to hit the over five times (all 10 of the games had set totals).
• The Dodgers are 6-4-0 against the spread over their past 10 games.

Dodgers Recent Stats

Dodgers Player Insights

• Shohei Ohtani paces the Dodgers in home runs (53) and runs batted in (99).
• Of all hitters in the majors, Ohtani's home run total ranks him third, and his RBI tally puts him 13th.
• Mookie Betts has 23 doubles, two triples, 20 home runs and 60 walks while batting .258.
• Betts ranks 79th in home runs and 52nd in RBI in the bigs.
• Freddie Freeman leads the Dodgers with a team-high batting average of .292.
• Freeman has at least one base hit in three straight games. During his last five outings he is hitting .211 with a walk and two RBIs.
• Andy Pages is batting .277 with 27 doubles, a triple, 25 home runs and 28 walks.

Dodgers Team Props

Diamondbacks Recent Betting Performance

• In five games as underdogs over the last 10 matchups, the Diamondbacks have a record of 4-1.
• In their last 10 games with a total, the Diamondbacks and their opponents have combined to hit the over five times.
• The Diamondbacks have seven wins against the spread in their last 10 chances.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Perdomo leads the Diamondbacks with 98 runs batted in while racking up a team-high batting average of .291.
• Among all hitters in the majors, Perdomo ranks 89th in home runs and 14th in RBI.
• Perdomo brings a hitting streak of 12 games into this game. During his last 10 outings he is hitting .395 with four doubles, a triple, a home run, six walks and five RBIs.
• Corbin Carroll has racked up a team-best 31 home runs.
• Among all major league hitters, Carroll ranks 15th in home runs and 37th in RBI.
• Ketel Marte has 26 doubles, 26 home runs and 63 walks while batting .280.
• Gabriel Moreno is batting .287 with 12 doubles, a triple, nine home runs and 26 walks.

Diamondbacks Team Props

Dodgers lose Ohtani gem game, Is Baseball in a good position right now? | The Herd

The Los Angeles Dodgers lost a game where Shohei Ohtani performed extremely well, as the New York Yankees and Seattle Mariners clinched playoff spots. Colin Cowherd discusses the state of baseball and if things are trending in the right direction.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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