Diamondbacks vs. Phillies Prediction, Odds, Picks - September 19

Kyle Schwarber and the Philadelphia Phillies head into a matchup with Corbin Carroll and the Arizona Diamondbacks on Friday at 9:40 p.m. ET. The favored Diamondbacks have -127 moneyline odds against the underdog Phillies, who are listed at +107. Arizona (-1.5) is the favorite on the run line. The over/under for the matchup has been set at 9 runs.

Here is everything you need from a betting perspective on the Diamondbacks-Phillies game, regarding the run line, moneyline and total, plus expert picks.

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Diamondbacks vs. Phillies Game Information & Odds

• When: Friday, September 19, 2025 at 9:40 p.m. ET
• Where: Chase Field in Phoenix, Arizona
• How to watch on TV: MLB Network, ARID, and NBCS-PH

Diamondbacks vs. Phillies Prediction

• Score Prediction: Diamondbacks 6, Phillies 5
• Total Prediction: Over 9 runs
• Win Probabilities: Diamondbacks 50%, Phillies 50%

Diamondbacks vs. Phillies Betting Insights

• This season, the Diamondbacks have won 45 out of the 87 games, or 51.7%, in which they've been favored.
• Arizona is 28-26 this season when entering a game favored by -127 or more on the moneyline.
• The moneyline for this contest implies a 55.9% chance of a victory for the Diamondbacks.
• The Phillies have been underdogs in 31 games this season and have come away with the win 15 times (48.4%) in those contests.
• Philadelphia has a mark of 10-9 in contests where sportsbooks favor it by +107 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Phillies have a 48.3% chance of pulling out a win.

Diamondbacks Recent Betting Performance

• The Diamondbacks played as the moneyline favorite for four of their last 10 games, and finished 2-2 in those matchups.
• Over their last 10 matchups (all had set totals), the Diamondbacks combined with their opponents to go over the total six times.
• The Diamondbacks' record against the spread is 5-5-0 over their past 10 games.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Geraldo Perdomo comes into Friday's game hitting .289 with 97 RBI, both team-leading marks for the Diamondbacks. He has also connected on 19 homers in 2025.
• Perdomo's home runs put him 81st in MLB, and he is 13th in RBI.
• Perdomo has collected a hit in eight games in a row. In his last 10 games he is batting .333 with two doubles, a triple, two home runs, eight walks and six RBIs.
• Carroll's 30 home runs are a team-high mark.
• Among all major league hitters, Carroll ranks 16th in homers and 48th in RBI.
• Carroll carries a four-game streak with at least one hit into this contest. During his last five outings he is hitting .333 with a double, a triple, five walks and two RBIs.
• Ketel Marte has 24 doubles, 25 home runs and 63 walks while batting .275.
• Gabriel Moreno is hitting .285 with 12 doubles, a triple, nine home runs and 24 walks.

Diamondbacks Team Props

Phillies Recent Betting Performance

• The Phillies have played as underdogs in four of their past 10 games and have gone 3-1 in those contests.
• In their last 10 games with a total, the Phillies and their opponents are 8-2-0 when it comes to hitting the over.
• The Phillies are 7-3-0 ATS over their last 10 games.

Phillies Recent Stats

Phillies Player Insights

• Schwarber leads the Phillies in home runs (53) and runs batted in (128).
• In all of the big leagues, Schwarber is second in home runs and first in RBI.
• Bryce Harper is hitting .263 with 32 doubles, 27 home runs and 66 walks.
• Among all major league hitters, Harper ranks 34th in home runs and 58th in RBI.
• Bryson Stott is hitting .257 with 20 doubles, three triples, 12 home runs and 52 walks.
• Nick Castellanos is hitting .252 with 27 doubles, two triples, 16 home runs and 31 walks.

Phillies Team Props

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