Cardinals vs. Blue Jays Prediction, Odds, Picks - June 11

The St. Louis Cardinals and Toronto Blue Jays will play on Wednesday at Busch Stadium, at 2:15 p.m. ET, with Brendan Donovan and Vladimir Guerrero Jr. -- two hot hitters -- expected to produce at the plate. The Cardinals are the favorite in this one, at -142, while the underdog Blue Jays have +119 odds to play spoiler. St. Louis is the run-line favorite (-1.5). The over/under for the game is listed at 8.5 runs.

Take a look at everything you need to know from a betting perspective on the Cardinals-Blue Jays game, regarding the run line, moneyline and total, plus expert picks.

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Blue Jays vs. Cardinals Highlights | MLB on FOX

Check out the best moments between the Toronto Blue Jays and the St. Louis Cardinals.

Cardinals vs. Blue Jays Game Information & Odds

• When: Wednesday, June 11, 2025 at 2:15 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to watch on TV: FDSMW and SNET

Cardinals vs. Blue Jays Prediction

• Score Prediction: Cardinals 5, Blue Jays 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Cardinals 54%, Blue Jays 46%

Cardinals vs. Blue Jays Betting Insights

• The Cardinals have been favorites in 29 games this season and won 15 (51.7%) of those contests.
• St. Louis has entered seven games this season favored by -142 or more and is 5-2 in those contests.
• The Cardinals have a 58.7% chance to win this game based on the implied probability of the moneyline.
• The Blue Jays have been chosen as underdogs in 41 games this year and have walked away with the win 22 times (53.7%) in those games.
• This year, Toronto has won four of nine games when listed as at least +119 or worse on the moneyline.
• The moneyline set for this matchup implies the Blue Jays have a 45.7% chance of walking away with the win.

Cardinals Recent Betting Performance

• The Cardinals played as the moneyline favorite for seven of their last 10 games, and finished 3-4 in those matchups.
• Over their last 10 outings (all had set totals), the Cardinals combined with their opponents to hit the over on the total seven times.
• The Cardinals are 4-6-0 against the spread over their past 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• Donovan has a team-best batting average of .310.
• Donovan's home runs rank him 193rd in MLB, and he ranks 116th in RBI.
• Nolan Arenado's eight home runs are a team-high mark.
• Among all MLB hitters, Arenado ranks 89th in homers and 55th in RBI.
• Lars Nootbaar has put up a team-best eight home runs.
• Willson Contreras has hit eight home runs with 42 runs batted in. Both pace his team.
• Contreras has recorded at least one hit in three games in a row. During his last five outings he is hitting .263 with a double, two home runs, two walks and six RBIs.

Cardinals Team Props

Blue Jays Recent Betting Performance

• The Blue Jays have played as underdogs in seven of their past 10 games and won five of those contests.
• In their last 10 games with a total, the Blue Jays and their opponents are 9-1-0 when it comes to hitting the over.
• Over their last 10 games, the Blue Jays are 5-5-0 against the spread.

Blue Jays Recent Stats

Blue Jays Player Insights

• Guerrero is hitting .275 with 12 doubles, eight home runs and 39 walks.
• Among all hitters in MLB, Guerrero is 89th in homers and 91st in RBI.
• Bo Bichette has driven in the most runs for the Blue Jays with 38 runs batted in.
• Bichette is currently 89th in homers and 35th in RBI in the major leagues.
• George Springer has 10 home runs, tops in the clubhouse.
• Alejandro Kirk leads the Blue Jays with a team-high batting average of .323.

Blue Jays Team Props

Blue Jays vs. Cardinals Highlights | MLB on FOX

Check out the best moments between the Toronto Blue Jays and the St. Louis Cardinals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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