Brewers vs. Reds Prediction, Odds, Picks - September 28

The Milwaukee Brewers and Cincinnati Reds meet on Sunday at 3:10 p.m. ET. Andrew Vaughn and Spencer Steer have been on a tear in recent games for their respective squads. The Reds have been listed as +111 moneyline underdogs for this matchup against the favored Brewers (-132). Milwaukee (-1.5) is favored on the run line. The matchup's total is set at 7.5 runs.

Here's everything you need from a betting perspective on the Brewers-Reds game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Brewers vs. Padres Highlights | MLB on FOX

Enjoy the best moments between the Milwaukee Brewers and the San Diego Padres.

Brewers vs. Reds Game Information & Odds

• When: Sunday, September 28, 2025 at 3:10 p.m. ET
• Where: American Family Field in Milwaukee, Wisconsin
• How to watch on TV: FDSWI and FDSOH

Brewers vs. Reds Prediction

• Score Prediction: Brewers 4, Reds 3
• Total Prediction: Over 7.5 runs
• Win Probabilities: Brewers 57%, Reds 43%

Brewers vs. Reds Betting Insights

• This season, the Brewers have been favored 96 times and won 59, or 61.5%, of those games.
• Milwaukee has a record of 44-18 in games when sportsbooks favor them by at least -132 on the moneyline.
• The moneyline for this contest implies a 56.9% chance of a victory for the Brewers.
• The Reds have won in 43, or 50.6%, of the 85 contests they have been named as odds-on underdogs this year.
• Cincinnati has a win-loss record of 19-30 when favored by +111 or worse by oddsmakers this year.
• The Reds have an implied victory probability of 47.4% according to the moneyline set for this matchup.

Brewers Recent Betting Performance

• The Brewers have a 3-6 record across the nine games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups -- all had a set run total -- the Brewers and their opponents combined to go over the total four times.
• The Brewers' record against the spread is 3-7-0 over their past 10 games.

Brewers Recent Stats

Brewers Player Insights

• Brice Turang is batting .287 with 27 doubles, two triples, 18 home runs and 64 walks.
• Turang's home runs rank him 105th in MLB, and he ranks 52nd in RBI.
• Turang carries a three-game hitting streak into this matchup. During his last five outings he is hitting .333 with a double, three walks and three RBIs.
• Christian Yelich has hit 29 home runs with 103 RBI. Both pace his team.
• Yelich ranks 33rd in home runs and 11th in RBI on the season.
• Yelich heads into this game looking for his sixth game in a row with a hit. In his last five games he is batting .238 with a double, three walks and three RBIs.
• William Contreras is batting .260 with 28 doubles, 17 home runs and 84 walks.
• Jackson Chourio is hitting .268 with 34 doubles, four triples, 21 home runs and 30 walks.

Brewers Team Props

Reds Recent Betting Performance

• The Reds have played as underdogs three times over their past 10 games and won each of those contests.
• In their last 10 games with a total, the Reds and their opponents have failed to hit the over eight times.
• The Reds have a record of 5-5-0 ATS over their last 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz leads the Reds in home runs (21) and runs batted in (85).
• De La Cruz's home run total places him 71st in the majors, and he ranks 39th in RBI.
• TJ Friedl is batting .260 with 22 doubles, two triples, 13 home runs and 80 walks.
• Friedl ranks 160th among all batters in the majors in homers, and 162nd in RBI.
• Steer has 21 home runs, best in the lineup.
• Austin Hays is hitting .266 with 16 doubles, five triples, 15 home runs and 29 walks.

Reds Team Props

Brewers vs. Padres Highlights | MLB on FOX

Enjoy the best moments between the Milwaukee Brewers and the San Diego Padres.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Milwaukee Brewers

Cincinnati Reds