Brewers vs. Angels Prediction, Odds, Picks - September 17

The Los Angeles Angels and Jo Adell take the field against Christian Yelich and the Milwaukee Brewers on Wednesday at American Family Field. The Brewers are -268 moneyline favorites for this matchup with the Angels (+217). Milwaukee is the run-line favorite (-1.5). The over/under for the matchup has been set at 7.5 runs.

Take a look at everything you need from a betting perspective on the Brewers-Angels game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Brewers vs. Angels Game Information & Odds

• When: Wednesday, September 17, 2025 at 7:40 p.m. ET
• Where: American Family Field in Milwaukee, Wisconsin
• How to watch on TV: FDSWI

Brewers vs. Angels Prediction

• Score Prediction: Brewers 5, Angels 3
• Total Prediction: Over 7.5 runs
• Win Probabilities: Brewers 62%, Angels 38%

Brewers vs. Angels Betting Insights

• The Brewers have been favorites in 87 games this season and won 56 (64.4%) of those contests.
• Milwaukee has been at least -268 moneyline favorites five times this season and won each of those games.
• Oddsmakers have implied with the moneyline set for this matchup that the Brewers have a 72.8% chance to win.
• The Angels have been chosen as underdogs in 114 games this year and have walked away with the win 51 times (44.7%) in those games.
• This season, Los Angeles has been victorious one time in four chances when named as an underdog of at least +217 or worse on the moneyline.
• The moneyline set for this matchup implies the Angels have a 31.5% chance of coming away with a victory in the contest.

Brewers Recent Betting Performance

• The Brewers were the moneyline favorite in nine of their last 10 games, and they went 6-3 in those matchups.
• In their last 10 matchups (all 10 of them had set totals), the Brewers and their opponents combined to go over the run total six times.
• The Brewers' ATS record is 5-5-0 over their past 10 games.

Brewers Recent Stats

Brewers Player Insights

• William Contreras is hitting .265 with 26 doubles, 17 home runs and 80 walks.
• Contreras ranks 103rd in home runs and 53rd in RBI among all hitters in MLB.
• Contreras has collected a hit in two straight games. In his last five games he is batting .333 with two walks and seven RBIs.
• Brice Turang is hitting .286 with 26 doubles, two triples, 18 home runs and 58 walks.
• Among all MLB hitters, Turang ranks 94th in homers and 56th in RBI.
• Turang carries a two-game streak with at least one hit into this contest. In his last five games he is batting .227 with a double, a home run, two walks and two RBIs.
• Yelich leads the Brewers in home runs (29) and runs batted in (99).
• Yelich will look to build on his two-game hitting in this game. In his last five games he is batting .227 with a double, two home runs and six RBIs.
• Jackson Chourio is batting .280 with 33 doubles, four triples, 20 home runs and 28 walks.

Brewers Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in seven of their past 10 games and won two of those contests.
• In their last 10 games with a total, the Angels and their opponents have failed to hit the over three times.
• The Angels have a record of 4-6-0 ATS over their last 10 games.

Angels Recent Stats

Angels Player Insights

• Taylor Ward has recorded a team-high 98 runs batted in.
• Ward's home run total places him 12th in MLB, and he is 11th in RBI.
• Adell's 36 home runs lead his team.
• Adell is eighth in homers and 14th in RBI among all major league hitters this season.
• Mike Trout is hitting .229 with 13 doubles, a triple, 21 home runs and 84 walks.
• Luis Rengifo is hitting .242 with 15 doubles, three triples, eight home runs and 33 walks.

Angels Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Milwaukee Brewers

Los Angeles Angels