Athletics vs. White Sox Prediction, Odds, Picks - April 25

Updated Apr. 25, 2025 10:00 p.m. ET

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The Athletics will send a hot-hitting Lawrence Butler to the plate against the Chicago White Sox and Andrew Vaughn, who has been on a tear in recent games, when the clubs square off on Friday at 10:05 p.m. ET. The White Sox are listed as +181 moneyline underdogs in this matchup against the favored Athletics (-219). The Athletics are favored on the run line (-1.5). The total is 9.5 runs for this matchup (with +103 odds on the over and -124 odds on the under).

Take a look at everything you need to know from a betting perspective on the Athletics-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Athletics vs. White Sox Game Information & Odds

• When: Friday, April 25, 2025 at 10:05 p.m. ET
• Where: Sutter Health Park in West Sacramento, California
• How to watch on TV: NBCS-CA and CHSN

Athletics vs. White Sox Prediction

• Score Prediction: Athletics 5, White Sox 4
• Total Prediction: Under 9.5 runs
• Win Probabilities: Athletics 58%, White Sox 42%

Athletics vs. White Sox Betting Insights

• The Athletics have won five of the eight games they've played as favorites this season.
• The Athletics have not entered a game this season with shorter moneyline odds than -219.
• Sportsbooks have implied with the moneyline set for this matchup that the Athletics have a 68.7% chance to win.
• The White Sox have come away with six wins in the 25 contests they have been listed as the underdogs in this season.
• This year, the White Sox have won two of 11 games when listed as at least +181 or better on the moneyline.
• The moneyline set for this matchup implies the White Sox have a 35.6% chance of coming away with a victory in the contest.

FINAL

CWS 5 · ATH 6

MLB

RUN LINE

TO WIN

TOTAL

Chicago White Sox

CWS

+1.5

+204

O 9.5

Athletics

ATH

-1.5

-249

U 9.5

Athletics Recent Betting Performance

• The Athletics have a 4-1 record over the five games they were a moneyline favorite in their last 10 matchups.
• In their last 10 outings (all had set totals), the Athletics combined with their opponents to go over the run total three times.
• The Athletics' ATS record is 6-4-0 over their past 10 games.

Athletics Recent Stats

Athletics Player Insights

• Tyler Soderstrom has racked up a team-high nine home runs and 21 runs batted in.
• Including all MLB hitters, Soderstrom ranks 35th in batting average, 50th in on-base percentage, and seventh in slugging.
• Soderstrom has collected a hit in two games in a row. During his last five outings he is batting .158 with two doubles, two walks and two RBI.
• Jacob Wilson's .330 batting average leads his team.
• Wilson is 131st in homers and 72nd in RBI in the major leagues.
• Wilson carries a two-game streak with at least one hit into this contest. During his last five outings he is hitting .316 with a walk and two RBI.
• Butler is hitting .271 with six doubles, four home runs and 13 walks.
• Butler will look to build on his three-game hitting in this game. In his last five games he is batting .190 with a double, two home runs, a walk and two RBI.
• Shea Langeliers is hitting .238 with four doubles, five home runs and nine walks.

Athletics Team Props

White Sox Recent Betting Performance

• In 10 games as underdogs over the last 10 matchups, the White Sox have a record of 2-8.
• The White Sox and their opponents have combined to hit the over four times in their last 10 games with a total.
• The White Sox have a record of 3-7-0 ATS over their last 10 games.

White Sox Recent Stats

White Sox Player Insights

• Andrew Sebastian Benintendi has swatted a team-high four long balls.
• In all of MLB, Benintendi ranks 49th in homers and 140th in RBI.
• Benintendi carries a four-game hitting streak into this matchup. In his last five games he is hitting .250 with a home run, two walks and two RBI.
• Luis Robert is hitting .138 with two doubles, two home runs and 13 walks.
• Robert is 131st overall in home runs and 214th in RBI this season.
• Miguel Vargas is batting .163 with five doubles, a home run and nine walks.
• Lenyn Sosa leads the White Sox with a team-leading batting average of .265.

White Sox Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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