Astros vs. Royals Prediction, Odds, Picks - May 14

Colton Gordon takes the mound for the Houston Astros on Wednesday at Daikin Park against Bobby Witt Jr. and the Kansas City Royals. First pitch is at 8:10 p.m. ET. The Astros are -125 moneyline favorites for this matchup with the Royals (+106). Houston (-1.5) is the favorite on the run line. The over/under for the game is set at 8.5 runs.

Check out everything you need from a betting perspective on the Astros-Royals game, regarding the run line, moneyline and total, plus expert picks.

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Astros' Isaac Paredes goes yard, belts a walk-off homer vs. Royals

The Houston Astros' Isaac Paredes went yard, belted a walk-off homer vs. the Royals.

Astros vs. Royals Game Information & Odds

• When: Wednesday, May 14, 2025 at 8:10 p.m. ET
• Where: Daikin Park in Houston, Texas
• How to watch on TV: SCHN and FDSKC

Astros vs. Royals Prediction

• Score Prediction: Astros 4, Royals 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Astros 61%, Royals 39%

Astros vs. Royals Betting Insights

• The Astros have entered the game as favorites 30 times this season and won 16, or 53.3%, of those games.
• Houston has entered 20 games this season favored by -125 or more and is 11-9 in those contests.
• Bookmakers have implied with the moneyline set for this matchup that the Astros have a 55.6% chance to win.
• The Royals have been underdogs in 25 games this season and have come away with the win 12 times (48%) in those contests.
• This year, Kansas City has won six of 16 games when listed as at least +106 or worse on the moneyline.
• The Royals have an implied victory probability of 48.5% according to the moneyline set by oddsmakers for this matchup.

Astros Recent Betting Performance

• The Astros have a 5-3 record from the eight games they were favored on the moneyline over their last 10 matchups.
• Over their last 10 matchups -- all had a set run total -- the Astros and their opponents combined to go over the total five times.
• The Astros' ATS record is 5-5-0 over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Jeremy Pena is the Astros best power option, connecting on six long balls this season in addition to delivering 21 RBI, both team highs.
• Of all batters in baseball, Pena ranks 64th in homers and 64th in RBI.
• Pena carries a six-game hitting streak into this matchup. During his last 10 outings he is hitting .349 with two doubles, two home runs, a walk and nine RBIs.
• Isaac Paredes is hitting .265 with six doubles, a triple, five home runs and 26 walks.
• Paredes is 88th in homers and 99th in RBI among all major league hitters this season.
• Jake Meyers leads the Astros with a .308 batting average.
• Meyers will look to build on his two-game hitting in this game. During his last five outings he is hitting .375 with a double, three walks and an RBI.
• Jose Altuve is hitting .263 with six doubles, four home runs and 11 walks.
• Altuve is riding a two-game hitting streak into this one. In his last five games he is batting .333 with two doubles and a walk.

Astros Team Props

Royals Recent Betting Performance

• In four games as underdogs over the last 10 matchups, the Royals have a record of 3-1.
• The Royals and their opponents have combined to hit the over four times in their last 10 games with a total.
• The Royals have a record of 6-4-0 ATS over their last 10 games.

Royals Recent Stats

Royals Player Insights

• Witt paces the Royals with 25 runs batted in while racking up a team-high batting average of .312.
• Witt's home run total puts him 88th in the majors, and he is 34th in RBI.
• Maikel Garcia has 10 doubles, a triple, four home runs and 17 walks while hitting .289.
• Garcia is 130th among all hitters in the big leagues in homers, and 115th in RBI.
• Vinnie Pasquantino leads the Royals in home runs (six) and runs batted in (25).
• Jonathan India is batting .245 with eight doubles, a home run and 21 walks.

Royals Team Props

Astros' Isaac Paredes goes yard, belts a walk-off homer vs. Royals

The Houston Astros' Isaac Paredes went yard, belted a walk-off homer vs. the Royals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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