Wyoming vs. Colorado State Prediction, Odds, Picks - October 25, 2025

Updated Oct. 25, 2025 3:04 p.m. ET

FOX Sports

The Bronze Boot is on the line when the Wyoming Cowboys (3-4) and the Colorado State Rams (2-5) square off on Saturday, October 25, 2025 at Jonah Field at War Memorial Stadium. The Cowboys are 4.5-point favorites. The contest's over/under is set at 46.5.

Last time out, the Cowboys fell to the Air Force Falcons, with 24-21 being the final score. Against the Hawaii Rainbow Warriors in their most recent game, the Rams lost 31-19.

Keep up with college football all season on FOX Sports.

Wyoming vs. Colorado State Game Information & Odds

When: Saturday, October 25, 2025 at 7:30 p.m. ET
Location: Jonah Field at War Memorial Stadium in Laramie, Wyoming
TV: CBS Sports Network
Live Box Score on FOX Sports

Wyoming vs Colorado State Betting Information updated as of October 25, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Wyoming	-4.5 (-110)	-195	+162	46.5	-109	-111

Wyoming vs. Colorado State Prediction

Pick ATS: Colorado State (+4.5)
Pick OU: Over (46.5)
Prediction: Wyoming 24, Colorado State 23

Predictions are made by the Data Skrive betting model.

Learn more about the Wyoming Cowboys vs. the Colorado State Rams game on FOX Sports!

Wyoming vs. Colorado State Betting Insights

Based on the spread and over/under, the implied score for the game is Cowboys 26, Rams 21.
The Cowboys have a 66.1% chance to claim victory in this contest based on the moneyline's implied probability. The Rams have a 38.2% implied probability.
Wyoming is 4-3-0 ATS this season.
Colorado State has won three games against the spread this season, failing to cover four times.

Wyoming vs. Colorado State: Head-to-Head

Over their last four meetings, Wyoming has totaled three wins versus Colorado State.
In their last four meetings, each team has covered two times with those contests eclipsing the total on one occasion.
Colorado State has been outpaced by 10 points in its last four tilts against Wyoming.

Wyoming vs. Colorado State: 2025 Stats Comparison

	Wyoming	Colorado State
Off. Points per Game (Rank)	20 (117)	21.9 (111)
Def. Points per Game (Rank)	22.6 (53)	27 (86)
Turnovers Allowed (Rank)	12 (116)	7 (37)
Turnovers Forced (Rank)	8 (70)	10 (40)

Wyoming 2025 Key Players

Name	Position	Stats
Kaden Anderson	QB	1,480 YDS (58.8%) / 9 TD / 6 INT
Samuel Harris	RB	398 YDS / 1 TD / 56.9 YPG / 5.8 YPC 13 REC / 158 REC YDS / 0 REC TD / 26.3 REC YPG
Chris Durr Jr.	WR	31 REC / 375 YDS / 3 TD / 53.6 YPG
Terron Kellman	RB	267 YDS / 4 TD / 38.1 YPG / 6.7 YPC 5 REC / 52 REC YDS / 0 REC TD / 10.4 REC YPG
Brayden Johnson	LB	31 TKL / 2 TFL / 1 SACK / 2 INT
Evan Eller	LB	33 TKL / 2 TFL / 1 SACK / 1 INT
Andrew Johnson	DB	32 TKL / 2 TFL / 1 SACK
Tyce Westland	DL	28 TKL / 3 TFL / 2 SACK

Colorado State 2025 Key Players

Name	Position	Stats
Jalen Dupree	RB	429 YDS / 2 TD / 61.3 YPG / 5.2 YPC 11 REC / 86 REC YDS / 0 REC TD / 14.3 REC YPG
Jackson Brousseau	QB	741 YDS (61.6%) / 6 TD / 0 INT 9 RUSH YDS / 1 RUSH TD / 1.8 RUSH YPG
Lloyd Avant	RB	328 YDS / 3 TD / 46.9 YPG / 5.8 YPC 8 REC / 49 REC YDS / 0 REC TD / 12.3 REC YPG
Armani Winfield	WR	19 REC / 261 YDS / 2 TD / 43.5 YPG
Owen Long	LB	76 TKL / 2 TFL / 1 SACK
Lemondre Joe	DB	26 TKL / 3 TFL / 2.5 SACK / 1 INT
Jake Jarmolowich	DB	38 TKL / 4 TFL / 1 SACK
Robert Edmonson	LB	29 TKL / 3 TFL / 1 SACK