Vanderbilt vs. Iowa Prediction, Odds, Picks - December 31, 2025

Vanderbilt vs. Iowa Prediction, Odds, Picks - December 31, 2025

Updated Dec. 29, 2025 3:05 p.m. ET
Data Skrive

The ReliaQuest Bowl features a battle between the Vanderbilt Commodores (who are 4-point favorites) and the Iowa Hawkeyes on December 31, 2025 at 12 p.m. ET on ESPN. The contest has an over/under of 46.5.

The Commodores' most recent contest was versus the Tennessee Volunteers, and they won by a score of 45-24. Last time out, the Hawkeyes defeated the Nebraska Cornhuskers, with 40-16 being the final score.

Keep up with college football all season on FOX Sports.

Vanderbilt vs. Iowa Game Information & Odds

  • When: Wednesday, December 31, 2025 at 12 p.m. ET
  • Location: Raymond James Stadium in Tampa, Florida
  • TV: ESPN
  • Streaming: FOX One + ESPN Bundle
Vanderbilt vs Iowa Betting Information updated as of December 29, 2025, 2:45 p.m. ET.
Favorite Spread (Odds) Favorite Moneyline Underdog Moneyline Total Over Moneyline Under Moneyline
Vanderbilt -4 (-110) -211 +175 46.5 -112 -108

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Vanderbilt vs. Iowa Prediction

  • Pick ATS: Iowa (+4)
  • Pick OU: Over (46.5)
  • Prediction: Iowa 27, Vanderbilt 26

Predictions are made by the Data Skrive betting model.

Learn more about the Vanderbilt Commodores vs. the Iowa Hawkeyes game on FOX Sports!

Vanderbilt vs. Iowa Betting Insights

  • Based on the spread and over/under, the implied score for the matchup is Commodores 25, Hawkeyes 21.
  • The Commodores have a 67.8% chance to collect the win in this contest per the moneyline's implied probability. The Hawkeyes have a 36.4% implied probability.
  • Vanderbilt has compiled a 10-2-0 record against the spread this season.
  • Iowa has covered eight times in 12 games with a spread this year.

Vanderbilt vs. Iowa: 2025 Stats Comparison

Vanderbilt Iowa
Off. Points per Game (Rank) 39.4 (12) 28.9 (67)
Def. Points per Game (Rank) 21.9 (34) 15.2 (6)
Turnovers Allowed (Rank) 12 (18) 11 (12)
Turnovers Forced (Rank) 14 (85) 14 (85)

Vanderbilt 2025 Key Players

Name Position Stats
Diego Pavia QB 3,192 YDS (71.2%) / 27 TD / 8 INT
826 RUSH YDS / 9 RUSH TD / 68.8 RUSH YPG
Sedrick Alexander RB 563 YDS / 11 TD / 46.9 YPG / 5.5 YPC
16 REC / 181 REC YDS / 4 REC TD / 16.5 REC YPG
Junior Sherrill WR 46 REC / 661 YDS / 7 TD / 55.1 YPG
Tre Richardson WR 41 REC / 683 YDS / 6 TD / 62.1 YPG
CJ Heard DB 60 TKL / 2 TFL / 2 SACK / 1 INT
Bryan Longwell LB 63 TKL / 6 TFL / 1 SACK / 1 INT
Miles Capers DL 32 TKL / 6 TFL / 4.5 SACK
Nicholas Rinaldi LB 38 TKL / 5 TFL / 3.5 SACK

Iowa 2025 Key Players

Name Position Stats
Mark Gronowski QB 1,529 YDS (62.5%) / 8 TD / 6 INT
491 RUSH YDS / 15 RUSH TD / 40.9 RUSH YPG
Kamari Moulton RB 783 YDS / 4 TD / 78.3 YPG / 5 YPC
15 REC / 95 REC YDS / 0 REC TD / 11.9 REC YPG
Kaden Wetjen WR 20 REC / 151 YDS / 1 TD / 13.7 YPG
Xavier Williams RB 260 YDS / 3 TD / 28.9 YPG / 5.9 YPC
Karson Sharar LB 76 TKL / 7 TFL / 2 SACK
Zach Lutmer DB 66 TKL / 5 TFL / 1 SACK / 3 INT
Xavier Nwankpa DB 68 TKL / 1 TFL / 1 INT / 1 PD
Koen Entringer DB 68 TKL / 3 TFL

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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