Tulane vs. Duke Prediction, Odds, Picks - September 13, 2025

Updated Sep. 13, 2025 3:04 p.m. ET

FOX Sports

The Duke Blue Devils (1-1) are only 1.5-point underdogs against the Tulane Green Wave (2-0) on Saturday, September 13, 2025. The total is 52.5 points for this matchup.

In their last game, the Green Wave won against the South Alabama Jaguars, 33-31. The Blue Devils' most recent contest was against the Illinois Fighting Illini, and they lost by a score of 45-19.

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Tulane vs. Duke Game Information & Odds

When: Saturday, September 13, 2025 at 8 p.m. ET
Location: Yulman Stadium in New Orleans, Louisiana
TV: ESPN2
Live Box Score on FOX Sports

Tulane vs Duke Betting Information updated as of September 13, 2025, 12:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Tulane	-1.5 (-111)	-123	+103	52.5	-110	-110

Tulane vs. Duke Prediction

Pick ATS: Tulane (-1.5)
Pick OU: Over (52.5)
Prediction: Tulane 30, Duke 24

Predictions are made by the Data Skrive betting model.

Learn more about the Tulane Green Wave vs. the Duke Blue Devils game on FOX Sports!

Tulane vs. Duke Betting Insights

Per the spread and over/under, the implied score for the matchup is Green Wave 27, Blue Devils 26.
The Green Wave have a 55.2% chance to win this meeting per the moneyline's implied probability. The Blue Devils hold a 49.3% implied probability.
Tulane has covered once in two matchups with a spread this season.
Duke has not won against the spread this year in two games with a spread.

Tulane vs. Duke: 2025 Stats Comparison

	Tulane	Duke
Off. Points per Game (Rank)	28 (75)	32 (62)
Def. Points per Game (Rank)	17 (58)	31 (103)
Turnovers Allowed (Rank)	1 (22)	6 (129)
Turnovers Forced (Rank)	7 (2)	0 (126)

Tulane 2025 Key Players

Name	Position	Stats
Jake Retzlaff	QB	277 YDS (56.4%) / 2 TD / 0 INT 177 RUSH YDS / 2 RUSH TD / 88.5 RUSH YPG
Zuberi Mobley	RB	100 YDS / 2 TD / 50 YPG / 6.3 YPC
Justyn Reid	TE	4 REC / 52 YDS / 1 TD / 26 YPG
Javin Gordon	RB	104 YDS / 0 TD / 52 YPG / 5.2 YPC
Jack Tchienchou	DB	15 TKL / 1 TFL / 1 SACK
Santana Hopper	DL	5 TKL / 1 TFL / 1 SACK
Javion White	DB	3 TKL / 0 TFL / 2 INT / 2 PD
Dickson Agu	LB	15 TKL / 0 TFL

Duke 2025 Key Players

Name	Position	Stats
Darian Mensah	QB	723 YDS (73.5%) / 5 TD / 1 INT
Andrel Anthony	WR	8 REC / 109 YDS / 3 TD / 54.5 YPG
Cooper Barkate	WR	9 REC / 205 YDS / 0 TD / 102.5 YPG
Sahmir Hagans	WR	8 REC / 87 YDS / 2 TD / 43.5 YPG
Vincent Anthony Jr.	DL	9 TKL / 4 TFL / 4 SACK
Kendall Johnson	LB	11 TKL / 2 TFL / 1 SACK
Nick Morris Jr.	LB	10 TKL / 3 TFL
Tre Freeman	LB	10 TKL / 2 TFL / 0.5 SACK