Texas Tech vs. Houston Prediction, Odds, Picks - October 4, 2025

Updated Oct. 4, 2025 3:04 p.m. ET

Data Skrive

The No. 11 Texas Tech Red Raiders (4-0) will test their second-ranked scoring offense against the Houston Cougars (4-0), who have the No. 59 scoring defense in the nation, on Saturday, October 4, 2025. The Red Raiders are favored by 13.5 points in the outing. The over/under for the game is set at 51.5.

Last time out, the Red Raiders defeated the Utah Utes, with 34-10 being the final score. The Cougars won versus the Oregon State Beavers in their most recent game, 27-24.

Keep up with college football all season on FOX Sports.

Texas Tech vs. Houston Game Information & Odds

When: Saturday, October 4, 2025 at 7 p.m. ET
Location: TDECU Stadium in Houston, Texas
TV: ESPN
Live Box Score on FOX Sports

Texas Tech vs Houston Betting Information updated as of October 4, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Texas Tech	-13.5 (-110)	-529	+394	51.5	-109	-111

Texas Tech vs. Houston Prediction

Pick ATS: Houston (+13.5)
Pick OU: Over (51.5)
Prediction: Texas Tech 34, Houston 21

Predictions are made by the Data Skrive betting model.

Learn more about the Texas Tech Red Raiders vs. the Houston Cougars game on FOX Sports!

Texas Tech vs. Houston Betting Insights

Based on the spread and over/under, the implied score for the tilt is Red Raiders 32, Cougars 19.
The Red Raiders have an 84.1% chance to collect the win in this contest per the moneyline's implied probability. The Cougars hold a 20.2% implied probability.
Texas Tech is 4-0-0 ATS this season.
Houston has won three games against the spread this year, failing to cover once.

Texas Tech vs. Houston: Head-to-Head

Over their last three meetings, Texas Tech has collected three wins against Houston.
The last three times the Red Raiders have gone up against the Cougars, they have put up a 2-1 record against the spread. The scoring has gone over the point total on two occasions.
Over their last three head-to-head contests, Texas Tech has put up 120 points, while Houston has accumulated 79.

Texas Tech vs. Houston: 2025 Stats Comparison

	Texas Tech	Houston
Off. Points per Game (Rank)	52 (10)	31.3 (81)
Def. Points per Game (Rank)	11.3 (5)	13.3 (9)
Turnovers Allowed (Rank)	5 (53)	1 (4)
Turnovers Forced (Rank)	9 (10)	6 (51)

Texas Tech 2025 Key Players

Name	Position	Stats
Behren Morton	QB	1,065 YDS (69%) / 11 TD / 3 INT
Cameron Dickey	RB	232 YDS / 6 TD / 58 YPG / 4.7 YPC 6 REC / 37 REC YDS / 0 REC TD / 12.3 REC YPG
J'Koby Williams	RB	201 YDS / 2 TD / 50.3 YPG / 5.2 YPC 12 REC / 222 REC YDS / 1 REC TD / 74 REC YPG
Will Hammond	QB	369 YDS (75.6%) / 4 TD / 1 INT 169 RUSH YDS / 2 RUSH TD / 42.3 RUSH YPG
Jacob Rodriguez	LB	20 TKL / 0 TFL / 1 INT / 1 PD
David Bailey	LB	8 TKL / 3 TFL / 3.5 SACK
Anthony Holmes Jr.	DL	11 TKL / 2 TFL / 1 SACK
Romello Height	LB	6 TKL / 2 TFL / 2.5 SACK

Houston 2025 Key Players

Name	Position	Stats
Conner Weigman	QB	839 YDS (61.3%) / 6 TD / 1 INT 144 RUSH YDS / 4 RUSH TD / 36 RUSH YPG
Dean Connors	RB	324 YDS / 3 TD / 81 YPG / 4.8 YPC 10 REC / 59 REC YDS / 0 REC TD / 14.8 REC YPG
Stephon Johnson Jr.	WR	8 REC / 235 YDS / 2 TD / 58.8 YPG
Tanner Koziol	TE	23 REC / 234 YDS / 2 TD / 58.5 YPG
Corey Platt Jr.	LB	6 TKL / 2 TFL / 2.5 SACK
Brandon Mack	LB	5 TKL / 0 TFL / 2 SACK
Will James	DB	7 TKL / 1 TFL / 1 INT / 1 PD
Eddie Walls III	DL	6 TKL / 2 TFL / 2 SACK