Tennessee vs. Oklahoma Prediction, Odds, Picks - November 1, 2025

Updated Nov. 1, 2025 3:04 p.m. ET

Data Skrive

The No. 18 Oklahoma Sooners (6-2) and the fifth-ranked scoring defense will visit the No. 14 Tennessee Volunteers (6-2) and the second-ranked scoring offense on Saturday, November 1, 2025. The Sooners are just 2.5-point underdogs. A total of 55.5 points has been set for this matchup.

Last time around, the Volunteers defeated the Kentucky Wildcats, with 56-34 being the final score. In their last contest, the Sooners lost against the Ole Miss Rebels, 34-26.

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Tennessee vs. Oklahoma Game Information & Odds

When: Saturday, November 1, 2025 at 7:30 p.m. ET
Location: Neyland Stadium in Knoxville, Tennessee
TV: ABC
Live Box Score on FOX Sports

Tennessee vs Oklahoma Betting Information updated as of November 1, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Tennessee	-2.5 (-116)	-141	+119	55.5	-105	-115

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Tennessee vs. Oklahoma Prediction

Pick ATS: Oklahoma (+2.5)
Pick OU: Over (55.5)
Prediction: Oklahoma 30, Tennessee 29

Predictions are made by the Data Skrive betting model.

Learn more about the Tennessee Volunteers vs. the Oklahoma Sooners game on FOX Sports!

Tennessee vs. Oklahoma Betting Insights

Based on the spread and over/under, the implied score for the tilt is Volunteers 29, Sooners 26.
The Volunteers have a 58.5% chance to claim victory in this meeting based on the moneyline's implied probability. The Sooners have a 45.7% implied probability.
Tennessee is 4-4-0 ATS this season.
Oklahoma has covered four times in eight games with a spread this year.

Tennessee vs. Oklahoma: 2025 Stats Comparison

	Tennessee	Oklahoma
Off. Points per Game (Rank)	45.6 (2)	28.4 (68)
Def. Points per Game (Rank)	30.9 (112)	12.5 (6)
Turnovers Allowed (Rank)	10 (68)	10 (68)
Turnovers Forced (Rank)	15 (13)	4 (131)

Tennessee 2025 Key Players

Name	Position	Stats
Joey Aguilar	QB	2,344 YDS (65.9%) / 18 TD / 6 INT 91 RUSH YDS / 2 RUSH TD / 13 RUSH YPG
DeSean Bishop	RB	652 YDS / 9 TD / 81.5 YPG / 7.2 YPC
Chris Brazzell II	WR	43 REC / 740 YDS / 8 TD / 92.5 YPG
Star Thomas	RB	418 YDS / 5 TD / 52.3 YPG / 5.6 YPC 6 REC / 58 REC YDS / 2 REC TD / 14.5 REC YPG
Arion Carter	LB	52 TKL / 2 TFL / 1 SACK
Joshua Josephs	DL	29 TKL / 3 TFL / 2 SACK
Colton Hood	DB	30 TKL / 3 TFL / 1 INT / 3 PD
Edwin Spillman	LB	47 TKL / 2 TFL / 1 SACK

Oklahoma 2025 Key Players

Name	Position	Stats
John Mateer	QB	1,790 YDS (63.6%) / 8 TD / 6 INT 226 RUSH YDS / 5 RUSH TD / 32.3 RUSH YPG
Isaiah Sategna	WR	43 REC / 624 YDS / 5 TD / 78 YPG
Tory Blaylock	RB	403 YDS / 4 TD / 50.4 YPG / 4.3 YPC
Xavier Robinson	RB	217 YDS / 3 TD / 43.4 YPG / 6 YPC 8 REC / 65 REC YDS / 1 REC TD / 13 REC YPG
R Mason Thomas	DL	20 TKL / 5 TFL / 5.5 SACK
Taylor Wein	DL	22 TKL / 10 TFL / 3.5 SACK / 1 INT
Kip Lewis	LB	31 TKL / 3 TFL / 0.5 SACK
Robert Spears-Jennings	DB	28 TKL / 1 TFL